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Author Topic: Eradicating HIV ?  (Read 1347 times)

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Offline manhattanman

  • Member
  • Posts: 19
Eradicating HIV ?
« on: May 19, 2007, 08:04:47 PM »
Did anyone see this article ?
Any insights from some of our memebers like HIV Worker who have much more in-depth knowledge than the lay people here ?
Would be curious.

http://www.bloomberg.com/apps/news?pid=20601087&sid=a.0x1mlV37Qw&refer=home

May have to cut and paste link

Offline 404error

  • Member
  • Posts: 431
Re: Eradicating HIV ?
« Reply #1 on: May 19, 2007, 10:05:00 PM »
I honestly don't feel that drug companies want to cure AIDS.  I think what they'd rather do is suggest that they're close, or have something they think "could" do it and then submit a press release on it.  That way they'll drive up interest in shares should they be a publicly traded pharmaceutical.  It would be in the best interest of big pharma, (in my estimation and speaking strictly from a business point of view), to develop a drug that eliminates the progession of the disease while at the same times blocks you from being able to pass it on to someone else.  If this drug could be made and turned into one pill that is taken once a day, the company would have millions of lifetime subscribers.  On the other hand, they could invent a cure inject you once and you'd be a customer who's been lost for life.  Are businesses in the general practise of trying to dwindle their customer base?  Not in my experience.  Also, big pharma have friends in much higher places than those living with the disease.  I'm not saying all of this is true (some of it definitely is) and I'm also not saying it's right. 
A social critic who promotes equality...

Offline BT65

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  • Vegas baby!
Re: Eradicating HIV ?
« Reply #2 on: May 19, 2007, 10:07:30 PM »
It would be good if they can do that, but it doesn't help me.  I've had HIV for too long.  But any stride forward helps I suppose.
I've never killed anyone, but I frequently get satisfaction reading the obituary notices.-Clarence Darrow

Offline milker

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  • Posts: 4,034
  • Protected phone sex
Re: Eradicating HIV ?
« Reply #3 on: May 19, 2007, 10:07:46 PM »
I haven't heard of any researcher complain that his boss said he was too close to find a cure for any disease. Who doesn't want a Nobel Prize?

Milker.
mid-dec: stupid ass
mid-jan: seroconversion
mid-feb: poz
mar 07: cd4 432 (35%) vl 54000
may 07: cd4 399 (28%) vl 27760
jul 07: cd4 403 (26%) vl 99241
oct 07: cd4 353 (24%) vl 29993
jan 08: cd4 332 (26%) vl 33308
mar 08: cd4 392 (23%) vl 75548
jun 08: cd4 325 (27%) vl 45880
oct 08: cd4 197 (20%) vl 154000 <== aids diagnosis
nov 2 08 start Atripla
nov 30 08: cd4 478 (23%) vl 1880 !!!!!!!!!!!!!!!!!!!!!!!!!!
feb 19 09: cd4 398 (24%) vl 430 getting there!
apr 23 09: cd4 604 (29%) vl 50 woohoo :D :D
jul 30 09: cd4 512 (29%) vl undetectable :D :D
may 27 10: cd4 655 (32%) vl undetectable :D :D

Now accepting applications from blowjob ninjas™

Offline otherplaces

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  • Posts: 398
  • Mutant Super Hero
Re: Eradicating HIV ?
« Reply #4 on: May 20, 2007, 12:49:43 AM »

Even if this was only for people who hit the meds right away I believe if they figured out a method that actually worked then you'd pretty much have all of the scientific community turn around and focus on improving one therapy which would begin to extend to those who didn't start therapy right away.  I think it'd be more than just a step in the right direction.

I tend not to jump in the cynical camp.  You can make that argument about treatment, but an HIV vaccine would be a windfall of proportions that drug company execs dream about every night when they go to sleep.  Think about it, vaccinating 6 billion people and every kid born until the patent runs out.  And vaccine research feeds into treatment research.




Offline Iggy

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  • Posts: 2,435
Re: Eradicating HIV ?
« Reply #5 on: May 20, 2007, 01:52:23 AM »
My serious issue with this article is that it doesn't address reservoirs of HIV outside of current accounting of it in the bloodstream.

I remember a recent series of articles that HIV may hide in the gut and that an undetectable viral load (according to blood tests) may have no relevance to the amount of HIV in your system.

I admit Fauci's appearance in this article gives me pause to not write off the whole thing - but I got to be upfront and say I think we are going to see a clarification on this report that is significantly different that what the original article portrays.

Offline Central79

  • Member
  • Posts: 527
Re: Eradicating HIV ?
« Reply #6 on: May 20, 2007, 08:08:51 AM »
There's another thread running on this here:

http://forums.poz.com/index.php?topic=12415.0
Diagnosed January 2006
26/1/06 - 860 (22%), VL > 500,000
24/4/06 - 820 (24.6%), VL 158,000
13/7/06 - 840 (22%), VL 268,000
1/11/06 - 680 (21%), VL 93,100
29/1/07 - 1,020 (27.5%), VL 46,500
15/5/07 - 1,140 (22.8%), VL not done.
13/10/07 - 759 (23.2%), VL 170,000
6/11/07 - 630 (25%), VL 19,324
14/1/08 - 650 (21%), VL 16,192
15/4/08 - 590 (21%), VL 40, 832

Offline HIVworker

  • Member
  • Posts: 918
  • HIV researcher
Re: Eradicating HIV ?
« Reply #7 on: June 03, 2007, 11:39:59 AM »
I think there are two schools of thought regarding how quickly the latent pool can be drained and the answer depends on who you talk to. Some say 7.7 years, some say 70 years. Experiments like this will decide who is right. My honest opinion is that HIV will be a harder nut to crack.

I obviously hope it is shorter, I just don't believe it will be.

R

« Last Edit: June 04, 2007, 10:28:27 PM by HIVworker »
NB. Any advice about HIV is given in addition to your own medical advice and not intended to replace it. You should never make clinical decisions based on what anyone says on the internet but rather check with your ID doctor first. Discussions from the internet are just that - Discussions. They may give you food for thought, but they should not direct you to do anything but fuel discussion.

 


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