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Author Topic: Any one using Darunavir?  (Read 1201 times)

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Offline scud44

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  • Posts: 393
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Any one using Darunavir?
« on: May 28, 2007, 05:12:08 AM »
My specialist is putting me on a regime of Darunavir, Retonavir, Abacavir and FTC (Fuzeon). Has any one else had this combination and if so with what results?
I will be starting in about 3 weeks - thats how long it takes to get some of the meds down here! ???
CD4 = 110 - 30 July 2007 - 10%
VL = 139000 - 30 July 2007
CD4 = 252 - 6th August 2007
VL = 16400 - 23rd August 2007
CD4 = 240 - 23rd August 2007
VL = 400 4th Sept 2007
CD4 = 96 - 4th Sept 2007
CD4 = 120 18th Sept 2007
VL = 386000 19th Nov 2007
CD4 = 160 19th Nov 2007
CD4 = 110 10th Jan 2008
CD4 = 311 29th Jan 2008
VL = <50 29th Jan 2008
CD4 = 148 2nd April 2008
VL = 110,000 2nd April 2008
June 2010 and nothing has improved

Offline allanq

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Re: Any one using Darunavir?
« Reply #1 on: May 29, 2007, 11:21:52 AM »
scud,

You stated that you're on "FTC (Fuzeon)." However, FTC is a nucleoside that is also known as Emtriva. Fuzeon is an entry inhibitor that is injected.

Are you on both those drugs?

I'm on Darunavir (also known as Prezista) and have found it pretty easy to take. I started darunavir to replace tipranavir (Aptivus), which had been giving me lots of problems with nausea and loss of appetite. Those problems went away after switching to darunavir.

Allan
Top (Breakfast): Prezista, Norvir, Isentress, Zoloft (2), Glyburide (2), Aspirin
Bottom right (Dinner): Prezista, Norvir, Isentress
Bottom left (Bedtime): Sustiva, Trazodone (2), Lipitor, Septra (no longer taking this)
Center: Alprazolam (Xanax)
Not shown: various vitamins & supplements

Offline scud44

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Re: Any one using Darunavir?
« Reply #2 on: May 29, 2007, 05:13:19 PM »
I am scheduled to start these in about 2 - 3 weeks - have to consult with GP again and confirm what he's doing
CD4 = 110 - 30 July 2007 - 10%
VL = 139000 - 30 July 2007
CD4 = 252 - 6th August 2007
VL = 16400 - 23rd August 2007
CD4 = 240 - 23rd August 2007
VL = 400 4th Sept 2007
CD4 = 96 - 4th Sept 2007
CD4 = 120 18th Sept 2007
VL = 386000 19th Nov 2007
CD4 = 160 19th Nov 2007
CD4 = 110 10th Jan 2008
CD4 = 311 29th Jan 2008
VL = <50 29th Jan 2008
CD4 = 148 2nd April 2008
VL = 110,000 2nd April 2008
June 2010 and nothing has improved

Offline Miss Philicia

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Re: Any one using Darunavir?
« Reply #3 on: May 29, 2007, 06:56:54 PM »
I've been on Prezista (Darunavir) and Fuzeon for exactly a year now.  My results have been PHENOMENAL.  I'm also on Truvada, which I had already been on previous to the Prezista/Fuzeon.  And of course one takes a Norvir booster with the Prezista.

They wanted me on Fuzeon 2 years ago, but my doctor decided to wait and get me on Prezista when it was available in a drug trial as preliminary results were showing a much more beneficial synergy with these two drugs as opposed to just taking them by themselves.  I think you'll be amazed with your results.  My cd4's doubled and are now at 973 or something, and my % went up to 43!  The main reason though that I went on this combo is that my VL has NEVER been undetectable for 13 years, but became undetectable within the first month and has remained so for the entire year.

I'm tempted to switch from the Fuzeon to one of the new things just now coming out because I get sick of doing the injections sometimes, but it's really not THAT bad most days.  So, I think I'll stick with it because I don't want to sacrifice my excellent numbers... sure, they could stay up that high with the new drugs but that is not assured, plus because Fuzeon does not pass through my digestive system my once extremely problematic diarrhea issues have vanished (well... I might have it still once a week -- must be the Norvir, but at least it's not every bowel movement like it was for a decade!!!)

The only question I have, mostly because I only took it for a month due to bad side effects about 8 years ago, is the Abacavir (Ziagen).  Not sure how that interacts with the other stuff.
"Iíve slept with enough men to know that Iím not gay"

Offline penguin

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Re: Any one using Darunavir?
« Reply #4 on: May 29, 2007, 07:05:41 PM »
yes, all of the above bar abacavir

darunavir, very easy to take, minimal if any side effects. If you are using it with fuzeon & other active drugs, I think you can expect to see excellent results.

as allan says, ftc & fuzeon are not same drug, very different,do check this.

good luck with new stuff - kate

*just as an aside... I will be dropping fuzeon for mk-0158 shortly...byebye, needles  :)  :)*

Offline MSPspud

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  • Posts: 613
  • Joined Mar 2005 - Formerly UofMurbs
Re: Any one using Darunavir?
« Reply #5 on: May 29, 2007, 08:51:00 PM »
I will just chime in to say, I've had great experience with Darunavir too.  Previously I was on Kaletra/Invirase and Epzicom.  It's a very potent drug with fewer side effects.

Best of luck!

Offline scud44

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  • Posts: 393
  • I am watching you
Re: Any one using Darunavir?
« Reply #6 on: May 29, 2007, 09:20:51 PM »
Thanks for the responses - I have a greater degree of confidence now - I will post results when available to see how they go
 :D
CD4 = 110 - 30 July 2007 - 10%
VL = 139000 - 30 July 2007
CD4 = 252 - 6th August 2007
VL = 16400 - 23rd August 2007
CD4 = 240 - 23rd August 2007
VL = 400 4th Sept 2007
CD4 = 96 - 4th Sept 2007
CD4 = 120 18th Sept 2007
VL = 386000 19th Nov 2007
CD4 = 160 19th Nov 2007
CD4 = 110 10th Jan 2008
CD4 = 311 29th Jan 2008
VL = <50 29th Jan 2008
CD4 = 148 2nd April 2008
VL = 110,000 2nd April 2008
June 2010 and nothing has improved

 


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