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Author Topic: Can a cold effect HIV Viral Load?  (Read 1748 times)

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Offline manchesteruk

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Can a cold effect HIV Viral Load?
« on: April 19, 2007, 02:47:52 PM »
I've been reading conflicting reports on the internet as always!  How about cold sores as well?
Diagnosed 11/05

"Life is too important to be taken seriously" Oscar Wilde

Offline ChaplinGuy

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  • Eat my left foot
Re: Can a cold effect HIV Viral Load?
« Reply #1 on: April 19, 2007, 03:36:46 PM »

Interesting you ask this, manuk, as I'm nursing a terrible one right now! I'm also curious to know the specifics of how common colds impact our VLs and CD4 counts - my understanding is it's not much, but affects each person a little differently (like everything else with this virus).

I do seem to be getting better (yesterday was awful), which makes me feel like my system is doing its job and fighting whatever it is off for now.

Offline keyite

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Re: Can a cold effect HIV Viral Load?
« Reply #2 on: April 19, 2007, 03:37:36 PM »
I remember my HIV doc saying the common cold does not affect VL. I've read (and she has confirmed) that herpes simplex - the virus responsible for cold sores - can negatively impact on HIV VL. It  For this reason we've agreed that I start a suppressive regime of acyclovir. Not sure, though, if this effect also applies to the oral type of herpes (as opposed to just the genital).

http://www.sciencedaily.com/releases/2007/02/070222160450.htm

Offline newt

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Re: Can a cold effect HIV Viral Load?
« Reply #3 on: April 19, 2007, 06:16:40 PM »
Active herpes (HSV) infection of some kinds is likely to raise viral load.  How much for you? Who knows... Why? Ah, good question.... Is it important? Depends... There is, anyhow, an intimate relationship between HIV/HSV replication.

One report, recent, on HSV-2, with references to explore

Abstract on HSV-1 and HIV activation

- matt
"The object is to be a well patient, not a good patient"

Offline milker

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Re: Can a cold effect HIV Viral Load?
« Reply #4 on: April 19, 2007, 07:25:47 PM »
Good presentation here too: http://www.ihmf.org/library/powerpoint/pp_k8_28.pps

As for the common cold, some modified rhinoviruses have been used in studies to induce HIV neutralization :)

Milker.
mid-dec: stupid ass
mid-jan: seroconversion
mid-feb: poz
mar 07: cd4 432 (35%) vl 54000
may 07: cd4 399 (28%) vl 27760
jul 07: cd4 403 (26%) vl 99241
oct 07: cd4 353 (24%) vl 29993
jan 08: cd4 332 (26%) vl 33308
mar 08: cd4 392 (23%) vl 75548
jun 08: cd4 325 (27%) vl 45880
oct 08: cd4 197 (20%) vl 154000 <== aids diagnosis
nov 2 08 start Atripla
nov 30 08: cd4 478 (23%) vl 1880 !!!!!!!!!!!!!!!!!!!!!!!!!!
feb 19 09: cd4 398 (24%) vl 430 getting there!
apr 23 09: cd4 604 (29%) vl 50 woohoo :D :D
jul 30 09: cd4 512 (29%) vl undetectable :D :D
may 27 10: cd4 655 (32%) vl undetectable :D :D

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