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Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

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Recent Posts

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81
Research News & Studies / Re: Has anybody heard of molecular scissors?
« Last post by JimDublin on Yesterday at 02:14:32 PM »
Glad to hear your looking at things from a positive (pardon me) point of view. 

I did not realize that there was a sub forum on this, im still learning all the ins and outs of this forum lol.
  Don't worry about it, some people never learn the ins and outs. Most of my day is spent moving stuff around, so your in good company. ;-)

Jim
82
Research News & Studies / Re: Has anybody heard of molecular scissors?
« Last post by Mints22 on Yesterday at 02:13:25 PM »
I honestly havent been reading up on a cure except for today when my friend said he heard something on the radio about it and i should check it out, thats why i wanted to ask after i read the article about it. But im taking my one pill a day right now and life hasnt changed much, besides my gf leaving, and me taking a pill everyday right now i feel the same. And am very hopeful and positive with the medicine. Once i get to UD and my cd4s come up ill be a little more relaxed since theres still a risk of pep. But im sure everything will be fine. And its really crazy to hear stories of years ago, and then today. Its some very good news to hear
83
Research News & Studies / Re: Has anybody heard of molecular scissors?
« Last post by Mints22 on Yesterday at 02:03:46 PM »
I did not realize that there was a sub forum on this, im still learning all the ins and outs of this forum lol. But yeah i agree its better to have a trial and fail than not trying at all. And in all honesty there could be a breakthrough tomorrow(just hypothetically of course) it could take some years. But the fact is that, with the new medicines out and the fact that they allow us to be undetectable and not transmit the virus is crazy(in the best way possible). From my first posts on here having heard stories from long term survivors, as well as newly infected persons, it gives me a lot of hope for the future with this. The major thing to combat is the stigma that has been placed upon it, atleast thats how i feel
84
Research News & Studies / Re: Has anybody heard of molecular scissors?
« Last post by JimDublin on Yesterday at 01:56:30 PM »
Look everybody tends to (in my opinion) slightly over do things at first trying to gain knowledge and often this tends to lead people to look for a "cure" and "cure" news.
It's understandable though, your new and trying to get your head around this.
 
Personally I take a pill a day and live my life. That's it.

I think the POZ article is a more fair update on this one. 23rd of May -  Seems like most research, this has given us a better insight into HIV but still no cure and no way near ready for humans, it had some limited success on rats it seems.

https://www.poz.com/article/researchers-use-crispr-edit-hiv-dna-live-animal-cells
Quote
The same researchers reported in March that they had successfully edited HIV DNA out of HIV-infected human cells in a laboratory setting. The paper led to a rash of erroneous media reports, stemming from an article in the United Kingdom’s The Guardian, claiming that a cure for HIV was only three years away.
 
Shortly after that paper was published, another research team put out a paper that found that HIV could become resistant to CRISPR/Cas9 gene editing, leading researchers to theorize that a multipronged gene-editing approach would be necessary to prevent such resistance.
 
The researchers in this new study injected the gene-editing apparatus into the rodents’ bloodstreams, and two weeks later analyzed the DNA in tissue samples from the animals. They found that the system had successfully snipped the targeted HIV fragment from more than half the cells of each type, including those in the tissues of the brain, heart, kidney, liver, lungs and spleen and in blood cells.
 
Analyzing the rats’ RNA, the investigators found that the gene editing had significantly lowered levels of viral RNA in circulating lymphocyte immune cells, as well as in the lymph nodes.
Jim
85
Research News & Studies / Re: Has anybody heard of molecular scissors?
« Last post by CaveyUK on Yesterday at 01:49:04 PM »
Yep, if you look through the sub-forum you will see references to this elsewhere.

It's good to be rooting for a cure, but if one does come it will likely be many years away as even if they found one tomorrow it would have to undergo years of research and clinical trials before being used.

Research is really important though, and when we do see a failure in the research thats actually a good thing as it contributes to overall knowledge and allows researchers to switch focus onto other techniques.

The thing to also remember is that modern meds can make the virus undetectable in your blood, render you unable to transmit the virus and allow your immune system to recover to normal levels allowing you to live a long and healthy life.

Yes, you are still HIV+ but thats damn near a functional cure on many levels already

86
Research News & Studies / Re: Has anybody heard of molecular scissors?
« Last post by JimDublin on Yesterday at 01:43:30 PM »
Hi

It's just research, not even new and it well, failed in a way but thats okay we even learn from the failures.  At the end of the day no cure or treatment unfortunately just bad/false reporting from the media. Here is the thread on this one: http://forums.poz.com/index.php?topic=62271.0

Media Outlets Falsely Claim That a Cure for HIV May Be Only Three Years Away
https://www.poz.com/article/media-outlets-falsely-claim-cure-hiv-may-three-years-away

Molecular scissors failed.
http://medicalxpress.com/news/2016-04-hiv-resistance-crisprcas9.html

Hang in there and keep taking you meds. You will see a lot of this type of research  come and go just don't get hooked on media headlines.

Hope you are doing okay.

Jim

87
Am I Infected? / Re: out of my mind with worry
« Last post by JimDublin on Yesterday at 01:30:07 PM »
Hi

Nothing you mentioned stood out as a risk. HIV is not transmitted like this.
Simply move on, continue to practice safer sex, use condoms & lube for intercourse and get tested at least yearly for all STI's including but not limited to HIV.

See HIV does not survive outside the human body, and it cannot reproduce outside a human host. Once hiv finds itself exposed outside the body to air, small changes in temperature, pH / moisture levels all quickly damage the virus and render it unable to infect.

Note that HIV also isn’t transmitted by hugging, shaking hands, sharing toilets, sharing dishes, kissing, through saliva, tears, or sweat

Here's what you need to know in order to avoid hiv infection:
You need to be using condoms for anal or vaginal intercourse, every time, no exceptions. As you are sexually active, it is highly recommended that you get a full sexual health check-up / screening at least annually including but not limited to hiv testing.

Remember that some sexual practices which may be described as ‘safe’ in terms of HIV transmission might still pose a risk for transmission of other STI's. So please do get fully tested regularly for all STI's including HIV and more frequently if unprotected intercourse occurs. Also note that it is possible to have an STI and show no signs or symptoms and the only way of knowing is by testing.

Finally use condoms for anal or vaginal intercourse, correctly and consistently, to avoid sexually transmitted hiv .

Kind regards

Jim

Please Note.
As a member of the AM I Infected Forum you are required to only post in this one thread no matter how long between visits or the subject matter. You can find this thread by going to your profile and selecting show own post and it will take you here . It helps us to help you when you keep all your thoughts or questions in one thread and it helps other readers to follow the discussion. Any additional threads will be deleted.
88
Research News & Studies / Has anybody heard of molecular scissors?
« Last post by Mints22 on Yesterday at 01:28:00 PM »
Hey everybody,
As i am newly diagnosed only a month in and 2 weeks on my triumeq treatment, i have been doing research and read an article online about molecular scissors being used as a cure, here is the article.
http://www.hivequal.org/hiv-equal-online/how-scientists-cut-hiv-out-of-its-hiding-spots-using-molecular-scissors

Im just wondering if anyone has any further knowledge about it or if their doctors have brought up anything up about molecular scissors?
89
Am I Infected? / out of my mind with worry
« Last post by tommatton on Yesterday at 01:12:43 PM »
i am a guy and got a nuru massage at a massage parlour..we were both fully nude and the girl was on my back, she was grinding me, her vagina touching my a$$...could i be at risk due to her vaginal fluids entering my a$$hole due to the direct contact between them
90
I Just Tested Poz / Re: Results back
« Last post by JimDublin on Yesterday at 01:07:54 PM »
Congratulations on the excellent results.
Enjoy the kayaking :-)

Jim
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