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Main Forums => Living With HIV => Topic started by: Tucsonwoody on February 13, 2007, 09:35:42 pm

Title: Effexor Withdrawal...what's your story?
Post by: Tucsonwoody on February 13, 2007, 09:35:42 pm
Hello everyone -

After deciding I wanted to go anti-depressant free, I recently finished the process of getting off of Effexor and was wondering if anyone else has done that and what your experience was like afterwards...emotionally, physically etc. Any feedback is appreciated.

Oh...and a merry Valentine's Day to you.
Title: Re: Effexor Withdrawal...what's your story?
Post by: sdcabincrew74 on February 13, 2007, 09:47:31 pm
Oh hell, that was one of the WORST experiences of my life.  I thought I was coming off crack or something!
Title: Re: Effexor Withdrawal...what's your story?
Post by: Boo Radley on February 14, 2007, 12:44:23 am
Woody,

Sorry, I can't offer any useful advice!

I was completely incapacitated by Effexor and took it only 4 days (at successively lower doses) before I stopped.  I felt like I was in the middle of a WWII battlefield or the house was going to collapse on me or something horrible was about to happen.   Effexor is a selective serotonin/norepinephrine reuptake inhibitor (SNRI) but it must have been norepinephrine part which caused the problems because SSRIs (which affect only serotonin) have worked best for me.

I've taken Paxil now for about 10 years and every so often I switch to another SSRI like Zoloft or Lexapro for 6 months or so and return to Paxil.  I've never had any side effects I couldn't deal with, although Zoloft eliminates my sex drive... but when you're living a chaste life that's not necessarily a bad thing...

Good luck!

Boo
Title: Re: Effexor Withdrawal...what's your story?
Post by: lydgate on February 14, 2007, 12:48:26 am
I've been on Effexor for 4+ years. I doubt I'll be coming off it anytime soon. But I'm very interested in hearing about how people have managed the taper and coming off it. I believe one common strategy is taking a dose (or three) of fluoxetine (Prozac), because of it's long half-life.

When I've missed a dose, just ONE DOSE, I've still had that horrible electric shocks out of my head feeling.

But it's been a very good drug for me. (Touch wood.)

Jay
Title: Re: Effexor Withdrawal...what's your story?
Post by: Cliff on February 14, 2007, 02:49:56 am
I was on it (well off and on it) a few years ago.  Coming off was always difficult, though it got better each time I needed to come off it.  The first time was the worst.  The analogy of a battlefield going off in your head was spot on.  It was absolutely horrible.  I can't remember how long it took, but I think it was at least a week and a half of sheer hell.  I learned from that experience that you just can't go off it cold turkey.  I would then do a dosage step down approach whenever I wanted to stop taking it.  Even taking it every other day once the dose was at the lowest level, before finally stopping all together.
Title: Re: Effexor Withdrawal...what's your story?
Post by: Christine on February 14, 2007, 04:48:48 pm
I was on it and developed Serotonin Syndrome probably from a reaction of Effexor and Norvir. I had to stop cold turkey. I felt like crap from the Serotonin syndrome; twitching, rash, fever. I also had the brain zaps.

The serotonin syndrome cleared up pretty fast- 3-4 days, but the brain zaps lasted a few weeks. I tried restarting the Effexor at a really low dose, but the twitching started again.

I was really pissed about it. Effexor worked extremely well for me.

Brain zaps were the main withdrawl effect for me.
Christine

Title: Re: Effexor Withdrawal...what's your story?
Post by: xtremepms on February 14, 2007, 08:06:34 pm
I went off of Effexor in November, and I still have vertigo "brain zaps" (Sums it up the best).  They are lessening by the day, now I only have them a few times a week. 

I thought about going back on it when my brother died, but did not want to go through the withdrawl again!
 
Good Luck!