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Author Topic: Interesting read  (Read 3617 times)

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Offline Delby

  • Member
  • Posts: 170
Interesting read
« on: January 16, 2014, 05:45:36 am »
http://au.ibtimes.com/articles/534368/20140115/hiv-cure-three-new-researches-dna-vaccine.htm#.Ute0CdLV_Yg

Obviously i am always very cautious when reading such articles, but there seems to be a lot of activity and research currently being undertaken. This is all very positive and i believe we will see new treatments being delivered in the next 10-15 yrs, that are more effective and tolerable. It may be even longer, but progress is being made and if we can all stay alive with the current run of drugs, then we have hope for our 'twilight' years.

Delby

Offline Battle4Hope

  • Member
  • Posts: 10
Re: Interesting read
« Reply #1 on: January 18, 2014, 08:33:43 am »
hoping against hope!!!!xciting research and progress....sincere thanx to all the scientist to stop this disease!!!

Offline mecch

  • Member
  • Posts: 13,455
  • red pill? or blue pill?
Re: Interesting read
« Reply #2 on: January 18, 2014, 09:08:00 am »
There is a lot of research going on for sure.  As there has been for two decades.

As a side note, that company IBT just bought Newsweek.  Let's hope they have better editors for a formerly important US weekly. Or, perhaps, the article you posted was quickly translated.  It's riddled with grammatical errors.

Anyway, these press releases by researchers are a dime a dozen. There are dozens of them a year, all worded more or less the same.  News aggregators pick them up and reprint them almost verbatim. Not sure what went wrong with this writer.

“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline xinyuan

  • Member
  • Posts: 202
Re: Interesting read
« Reply #3 on: January 18, 2014, 07:50:00 pm »
I'm going to be very frank. Most studies may be interesting but are clinically worthless. Except when they make it to human trials. And even those are fraught with failures. Most test tube, tissue, and animal studies are practically a dime a dozen.

In other words, it's really not worth paying attention to most studies for us patients. Unless they survive getting to human beings.

That being said, I'm greatly impressed with what has made it so far.

Offline Dr.Strangelove

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  • Posts: 215
Re: Interesting read
« Reply #4 on: January 20, 2014, 07:55:24 am »
I wouldn't say worthless, but yes many studies are basic science that will not directly lead to any clinical trials. Unfortunately, news articles often suggest otherwise.

Offline Jmarksto

  • Member
  • Posts: 667
Re: Interesting read
« Reply #5 on: January 20, 2014, 10:06:24 am »
I'm going to be very frank. Most studies may be interesting but are clinically worthless. Except when they make it to human trials. And even those are fraught with failures. Most test tube, tissue, and animal studies are practically a dime a dozen.

In other words, it's really not worth paying attention to most studies for us patients. Unless they survive getting to human beings.

That being said, I'm greatly impressed with what has made it so far.

I agree with all of this....the challenge is that funding tends to be directed towards labs that are working on "breakthrough" projects, and the scientific journals favour the sensationalist -- which tends to force the labs to oversell the clinical viability of their work.   

This article from the Economist does a very good job of outlining some of the problems we are having with the scientific process:

http://tinyurl.com/Economist-Science-Article
03/15/12 Negative
06/15/12 Positive
07/11/12 CD4 790          VL 4,000
08/06/12 CD4 816/38%   VL 49,300
08/20/12 Started Complera
11/06/12 CD4   819/41% VL 38
02/11/13 CD4   935/41% VL UD
06/06/13 CD4   816/41% VL UD
10/28/13 CD4 1131/45% VL 25
02/25/14 CD4   792/37% VL UD
07/09/14 CD4 1004/39% VL UD
11/03/14 CD4   711/34% VL UD
03/13/15 CD4   833/36% VL UD
04/??/15 Truvada & Tivicay
06/01/15 CD4 1100/50% VL UD
10/16/15 CD4   826/43% VL UD
??/??/2017 Descov & Tivicay
2017 VL UD, CD4 stable around 850
2018 VL UD, CD4 stable around 850

 


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