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Author Topic: effective treatment hiv anti-CTLA4 - MDX-1106?  (Read 4544 times)

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Offline brazilianman

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effective treatment hiv anti-CTLA4 - MDX-1106?
« on: July 07, 2009, 04:02:40 pm »
 ??? ??? ???the two antibodies already exist, need not be manufactured. has proved safe in tests on humans. Why not test HIV positive in humans? ??? ??? ???
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Offline brazilianman

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  • Posts: 92
Re: effective treatment hiv anti-CTLA4 - MDX-1106?
« Reply #1 on: July 07, 2009, 06:45:14 pm »
pipeline medarex

Strategic Assets in Clinical Development

Product Candidate Indication Clinical Status Partner/Licensee
Ipilimumab
anti-CTLA4 Melanoma, Prostate Cancer, Lung Cancer and Others  Phase 3 and earlier Bristol-Myers Squibb
Co-promote/Profit share
MDX-1100
anti-IP10 Ulcerative Colitis, Rheumatoid Arthritis Phase 2 Wholly-owned
 
MEDI-545 and MEDI-546
anti-IFNα Pathway Lupus and Autoimmune Diseases Phase 2 and earlier MedImmune/AstraZeneca
Co-promote option
MDX-1342
anti-CD19 Chronic Lymphocytic Leukemia, Rheumatoid Arthritis Phase 1 Wholly-owned
 
MDX-1106 (ONO-4538)
anti-PD1 Cancer, Hepatitis C Phase 1 Ono Pharmaceutical
Co-development
MDX-1105
anti-PD-L1 Cancer Phase 1 Wholly-owned
 
MDX-1401
anti-CD30 Hodgkin Lymphoma Phase 1 Wholly-owned
 
MDX-1411
anti-CD70 Cancer Phase 1 Wholly-owned
 
MDX-1203
anti-CD70 Antibody-Drug Conjugate Cancer Phase 1 Wholly-owned
 
ValortimTM (MDX-1303)
anti-B. anthracis PA Anthrax Infection Phase 1 PharmAthene
Co-development

Selected Financial Assets in Late-Stage Clinical Development

Product Candidate Indication Clinical Status Partner/Licensee
STELARATM (ustekinumab)
anti-IL12/IL23 Psoriasis Approved in Canada and Europe Centocor Ortho Biotech
Milestones/Royalties
SIMPONITM (golimumab)
anti-TNFα Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis Approved in Canada and U.S. Centocor Ortho Biotech
Milestones/Royalties
Ilaris® (canakinumab)
anti-IL1β Cryopirin-associated Periodic Syndromes Approved in U.S. Novartis Pharma
Milestones/Royalties
Ofatumumab (HuMax-CD20)
anti-CD20 Chronic Lymphocytic Leukemia, Rheumatoid Arthritis BLA/MAA Filed Genmab/GlaxoSmithKline
Equity Interest
Zalutumumab (HuMax-EGFR)
anti-EGFR Head and Neck Cancer Phase 3  Genmab
Equity Interest
MDX-066 (CDA-1) +
MDX-1388 (CDA-2)
anti-C. difficile Toxin A and Toxin B C. difficile Infection Phase 2 Merck & Co.
Co-development
« Last Edit: July 07, 2009, 06:47:16 pm by brazilianman »
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