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Author Topic: Chinese scholars announce breakthough in HIV virus study  (Read 3130 times)

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Offline GoForIt

  • Member
  • Posts: 214
Chinese scholars announce breakthough in HIV virus study
« on: January 09, 2014, 10:11:22 am »
http://www.globaltimes.cn/content/836648.shtml#.Us67L7TwDP0

Chinese researchers said they have made a significant breakthrough in the structural analysis of the viral infectivity factor (Vif) of the HIV virus, which will help in the development of new medications to treat or even cure the disease.

The new research was published on the website of science journal "Nature" on Wednesday. It was carried out by a team of Chinese researchers led by Huang Zhiwei, professor of structural molecular biology with the School of Life Science and Technology at Harbin Institute of Technology.

The research reveals the structural analysis of HIV-1 protein Vif, whose role is to subvert antiviral activity.

The results lay a foundation for the design of novel anti-HIV drugs, the paper said. The Chinese team launched the research program in March 2012.

Ever since the AIDS virus was discovered in 1981, people have had insufficient knowledge of the virus itself, including the structure of Vif, which is extremely important to virus infection and replication, said Huang.

Analyzing Vif structure is vital to the design of AIDS treatment medicines, Huang added.

The study of Vif structure has been the most important subject for scientists worldwide on AIDS in recent years.

China is the first to come out with research achievements on the subject, showing it is at the forefront of structural molecular biology study in AIDS, according to Huang.

The research team has begun cooperation with drug producers to develop new types of medicines for treating AIDS, Huang told Xinhua on Thursday.

"After medicine development succeeds, it will break a new path for treating AIDS worldwide, even hopefully curing it," Huang said, adding that it will also pave the way for Chinese-made drugs to fight HIV/AIDS.

China has about 434,000 people living with HIV/AIDS, according to government statistics. Worldwide, the number reached about 35 million at the end of 2012.
08/09/2013  Diagnosed WB positive
08/20/2013  CD4-506(28%)  VL-10,800
09/12/2013  CD4-391(28%)  VL-14,900
09/17/2013  Start ART (Truvada + Tivicay)
10/11/2013  CD4-377(26%)  VL-UD
12/20/2013  CD4-590(??%)  VL-UD
03/18/2014  CD4-660(29%)  VL-UD
07/22/2014  CD4-613(29%)  VL-UD
08/01/2014   Start Phase 3 TAF (Truvada 2.0) Clinical Trial (TAF + Tivicay)
10/09/2014  CD4-498(29.5%) VL-UD
11/06/2014  CD4-600(30.2%) VL-UD
01/30/2015  CD4-529(31.3%) VL-UD
07/25/2015  CD4-742(36.5%) VL-UD
10/06/2015  CD4-765(28.9%) VL-UD
01/05/2016  CD4-907(33.1%) VL-UD
03/24/2016  CD4-770(33.5%) VL-UD
06/20/2016  CD4-850(35.4%) VL-UD

Dr. Mark Wainberg on Dolutegravir:
Video 1: https://youtu.be/wCXOgLJqJAY
Video 2: https://youtu.be/DKiaD7fHO-s

Offline xinyuan

  • Member
  • Posts: 202
Re: Chinese scholars announce breakthough in HIV virus study
« Reply #1 on: January 13, 2014, 02:07:24 pm »
I'm thrilled that it was published in Nature.

As with any research study, their findings on the Vif structure must be replicated and verified by other labs, though.

ESPECIALLY, coming from China. Sorry and not to generalize, but the mainland Chinese have already earned an unsavory reputation for faking research.

http://www.nature.com/nature/journal/v441/n7093/full/441549b.html

http://www.nytimes.com/2010/10/07/world/asia/07fraud.html?pagewanted=all&_r=0

 


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