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Main Forums => Living With HIV => Topic started by: sanitex on December 01, 2009, 11:20:29 pm

Title: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 01, 2009, 11:20:29 pm


hello guys, been on sustiva,tenofovir,lamuvidine,for almost a year and 9 months then just change
to (sustiva,Truvada)2months ago i began to have more anxiety even to the extend that i could
not drive again same i used to drove before. but i still taken my anxiety meds(lexapro,tranxene,haldol).

now,i'm feeling depressed everyday even to go to exercise  i don't know who to blame the sustiva or hiv
itself.so i want to throw this problem to this forum to help me decide what to do if to change my sustiva or
what else to do.

for me  i like this regimen but due to this plight i'm having i don't know what else can be less side effects
like sustiva in times of liver toxicity and others. has anyone experienced the side effects of Viramune?mostly
i need combo that can be taking once at bed time that can go with TRUVADA not more three tabs a night.
pls any advice should appreciate thanks .sanitex

Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 02, 2009, 10:27:45 pm
h! everyone

                          today i feel like my head is turning round as if i've to bend
my head to my back and get my brain back in control and  feeling dizziness as well.i'm tired of
this problem .
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 03, 2009, 10:42:57 am

for me  i like this regimen but due to this plight i'm having i don't know what else can be less side effects
like sustiva in times of liver toxicity and others. has anyone experienced the side effects of Viramune?mostly
i need combo that can be taking once at bed time that can go with TRUVADA not more three tabs a night.
pls any advice should appreciate thanks .sanitex



As far as finding out about people's experiences with Viramune, it would be easier to find if you start a specific thread about that in the Treatment & Side Effects forum or if you do a search for Viramune and see what comes up.

It's difficult to recommend a specific alternative combo without knowing your treatment history or your resistance profile or what is available in your country.

The new US Guidelines came out and there are 4 "Preferred Options," for those starting meds. Atripla is one of them. Even though you are not just starting, if you are switching due to side effects, as opposed to switching due to treatment failure, you may be able to use one of the three other options (outside of Atripla), this is something you have to make sure with your doctor but these are the options:

Reyataz/Norvir/Truvada
Prezista/Norvir/Truvada
Isentress/Truvada (this is twice a day but it is an excellent combo)

LINK:

http://www.aidsmap.com/en/news/90025212-9B46-4408-A81B-AC8719FB6CDF.asp
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 03, 2009, 11:43:13 pm
hello Inchlinblue
                           my dear thanks for your concern towards my problem i really appreciate it
much and remain bless with your kind.anyway here is what DR Gallant sent to me also almost
the same as you mentioned,regards to resistance i've not had any problem before or change
any combo but due to anxiety i feel like to do something else to get myself back .but i need to
check about the combos in thailand and i do hope it's not yet available in thailand
On Dec 2, 2009 Joel E. Gallant, M.D., M.P.H. replied:

--------------------------------------------------------------------------------
It's worth trying a switch to something else to see if the problem gets better: it's the only way to know whether the medications are causing this or making it worse. When this happens, I usually switch patients to Truvada plus Prezista/Norvir, which can be taken once a day with food. (2 tabs of Prezista 400 mg, 1 cap of Norvir 100 mg, and 1 Truvada). Other options are Truvada plus Reyataz (300 mg) and Norvir (100 mg) once a day, or Truvada once a day plus Isentress 400 mg 1 tab twice a day.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 04, 2009, 12:23:13 am
You should be able to find something that works better for you.  

Keep us posted on what happens. ;)

 
Remember that even though you are having a hard time you should still continue with Atripla until you have your new combo, so you don't have the risk of developing resistance.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: esper on December 04, 2009, 09:05:08 am
hi sanitex, sorry you're have a tough time. Unfortunately, Isentress is not currently available in Thailand, according to my doc at Bumrungrad. Isentress was acually my first choice, after researching all the combos (Inch, I believe you are taking it with good result??) , but can't get it here yet. Not sure about reyataz and prezista, but they've been around a while and I think most of the usual combo components are here. I'm starting on sustiva and truvada next week. good luck. esper
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 04, 2009, 10:22:20 am
(Inch, I believe you are taking it with good result??)

Yes, so far so good. I started in July. I don't have any side effects, I just hope there are no long-term ones. Basically I feel great, went undetectable very quickly. Will have new lab work done on 12/15.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: esper on December 04, 2009, 08:54:51 pm
Inch, everything I've read is that Isentress is very effective and very little, normally, for immediate side effects. Long-term effects I guess is still a question. I'll look forward to seeing your next lab results. If/when it comes to thailand, and depending on how I'm doing with my combo and my doc's advice, I may switch from the Viraday or Truvada/Sustiva combo I'm going on. Glad its working for you!!

Also, Sanitex, I found this link on the thaivisa.com/forums site giving list of available ART drugs and their price at the Thai Red Cross Anon Clinic. Its an updated list, according to the poster on that site, from November. Here's the link.  Both Reyataz and Prezista are there. hope this helps.

http://www.thaivisa.com/forum/Hiv-Treatment-Los-Doctors-Meds-t285198.html
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 05, 2009, 01:05:49 am

             esper and Inchlinblue thanks for you guys reply and showing concern towards this, i really
appreciate it much .anyway i will meet my ID doc next week if this continue much.
but esper how about those combo side effect and moreover do you live in thailand as i
do?i have read the information you posted i was supprise to hear that they have all those
meds here already and my ID doc always recomened  that( Anno clinic )for me to get some
meds cheap there but due to the stigma following the disease i felt like buying it from private
hospital.thakx
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: esper on December 05, 2009, 09:55:11 pm
Hi sanitex, glad the info was helpful. yes I stay in thailand. I haven't been to the Thai Red Cross "Anon clinic" myself yet, but probably will go in the next few months. I went to their web site today, the cd4 test only costs 400 baht, the VL test is 3000 baht, much cheaper than what i pay at Bumrunrad.  the web site says can only get the cd4 test on friday from 830 am til noon.

the list of meds from the anon clinic, I was surprised, doesn't show FTC (emtricitibine, sold as Emtriva, the other component of Truvada), so I am going to check with them next week. Also Viraday isn't shown, which is the generic Atripla. by the way, I'm no expert, I'm just starting meds myself next week, will buy from Bumrungrad at least initially.  but the anon clinic info is good to know at least for comparison. good luck. esper
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 07, 2009, 12:17:24 am
h! Esper
                i thought they have (Truvada) as well but i don't think the price of viral load
 was not what you mentioned here i due hope is more less than that price cause (Sustiva,Truvada)
for 2months is almost 5500baht iicluding checkind cd4 and vira load about (7500baht)
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: esper on December 07, 2009, 11:45:54 pm
Hi Sanitex, I called the anon clinic today, they confirm they have truvada (not sure if generic version), its 70 baht per pill. Stocrin is 27 baht per pill (so for 30 days combined for both is 2910 baht). They do not sell Viraday (generic Atripla). The cd4 and VL test cost I am just quoting from their web site (if it is correct, its a little more than half of the cost for these tests at Bumrungrad). I am going to go check the clinic out next week, will post what I find out.  esper
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 08, 2009, 12:06:25 am



  h! Esper,i hope the Truvada is the generic one it's the original one suppose to be from USA.esper it seems
like you're not living here before or you just come new in thailand?anyway you can e-mail me if you won't
mind on mab71@yahoo.com.ok then let me know your new update for the price of this meds(Reyataz/Norvir/Truvada)
Prezista/Norvir/Truvada
Isentress/Truvada (this is twice a day but i don't know if it's available now there)

Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: esper on December 08, 2009, 09:56:42 pm
hi sanitex, I sent you a PM. as I posted before, as far as I know / am told, Isentress is not available here. i don't have any other price info on the combos you mention, probably what was posted in thaivisa forum is latest.  esper
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 09, 2009, 12:12:31 am



 H! esper thanks for the info and i'will get bact you soon,and inchlinblue pls read this post and reply back
to me,

          is't possible to switch to any of the combos you mentioned even if there's any big side efects i can switch back to sustiva ?thakx pls reply
   
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 09, 2009, 12:41:49 pm

 
          is't possible to switch to any of the combos you mentioned even if there's any big side efects i can switch back to sustiva ?thakx pls reply
   

Yes but only if you are undetectable.

If you are undetectable, you can stop one combo one day and start the next combo the next day.

I am not familiar with your treatment history, you must also make sure that you are not resistant to the new meds you are switching to.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 10, 2009, 01:05:38 am
Yes but only if you are undetectable.

If you are undetectable, you can stop one combo one day and start the next combo the next day.

I am not familiar with your treatment history, you must also make sure that you are not resistant to the new meds you are switching to.

h! Inchlinblue i've not been on any of those medication you mentioned since i was diagnosed,i'm only
on sustiva,tenofovir,lamuvidine,then only change Truvada, i don't know if i  suppose to check  my
resistance issue before switching to any new combo? but i do hope my last test was undetectable by>40copise.
thanks
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 10, 2009, 10:30:27 am
h! Inchlinblue i've not been on any of those medication you mentioned since i was diagnosed,i'm only
on sustiva,tenofovir,lamuvidine,then only change Truvada, i don't know if i  suppose to check  my
resistance issue before switching to any new combo? but i do hope my last test was undetectable by>40copise.
thanks

It's not possible to do a resistance test with an undetectable viral load, most resistance tests need at least 1000 copies/mL viral load.

Since you would be switching to a boosted PI or an integrase inhibitor (with Truvada) chances are it's fine, unless you originally contracted a virus that had heavy PI mutations which is very unlikely. And having any mutations to inegrase would be impossible since it's such a new class.

Have you been able to find the alternate medications? Have you decided which ones to switch to?
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 11, 2009, 02:02:03 am

! Inchlinblue ,i've not decide but i due hope this combo will be nice hence i'll not refrigerated it(Prezista/Norvir/Truvada)
what do you think?but i'm tring to work towards the price that's the big problem here in thailand.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 11, 2009, 02:03:29 am
It's not possible to do a resistance test with an undetectable viral load, most resistance tests need at least 1000 copies/mL viral load.

Since you would be switching to a boosted PI or an integrase inhibitor (with Truvada) chances are it's fine, unless you originally contracted a virus that had heavy PI mutations which is very unlikely. And having any mutations to inegrase would be impossible since it's such a new class.

Have you been able to find the alternate medications? Have you decided which ones to switch to?
! Inchlinblue ,i've not decide but i due hope this combo will be nice hence i'll not refrigerated it(Prezista/Norvir/Truvada)
what do you think?but i'm tring to work towards the price that's the big problem here in thailand.

Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 11, 2009, 10:08:16 am
! Inchlinblue ,i've not decide but i due hope this combo will be nice hence i'll not refrigerated it(Prezista/Norvir/Truvada)
what do you think?but i'm tring to work towards the price that's the big problem here in thailand.



Norvir is the one that needs to be refrigerated but not if you use it within 30 days.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Desertguy on December 11, 2009, 10:18:32 am
Viramune & Travuda!!!!

I had to get off Atripla for the same reason
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 11, 2009, 10:39:33 am
Viramune & Travuda!!!!

I had to get off Atripla for the same reason

Viramune has an unusual dosing schedule when starting out, doesn't it?
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: leatherman on December 11, 2009, 11:21:09 am
but not if you use it within 30 days.
that's not totally true. ;)
it also depends on the ambient temp and temperature changes of where you live
Trust me. :D

Even in an Ohio summer, leaving norvir out of the refrigerator for several days can lead to a bottle of melted goop. ::) And in reverse, I've nearly had it freeze up in an Ohio winter sitting in a cold bathroom medicine cabinet. :o (I wasn't just whistling Dixie when I said I moved back South because I hated the blizzards :D)

I learned to keep it in my frig continually - after I got the temp adjusted in there to not be cold enough to freeze the gelcaps ;) - because that's where the temp in my house was least variable.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: joemutt on December 11, 2009, 08:55:22 pm
I am on Truvada and Neravir, the latter a Thai government produced generic of nevirapine.
I get them at anonymous clinic, but you need to bring a prescription with you to buy them.
The Truvada is the US brand, not generic but the price @ 70thb/pill is ok, much less than private hospitals.
I dont feel much stigma at anonymous clinic, everyone there has hiv, lol.
Testing and labs are good there, though again you need a doctor outside to evaluate the results.
Hope this helps.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 11, 2009, 11:41:42 pm
 Liver problems have been reported in HIV-positive people treated with Viramune. The greatest risk of liver problems is during the first six weeks of treatment. Liver problems are more likely to occur in women (including pregnant women) with CD4 cell counts greater than 250 at the time of starting HIV treatment for the first time. As for men, liver problems are more likely to occur if the CD4 cell count is above 400 at the time of starting HIV treatment for the first time. HIV-positive people should work with their doctors very carefully if they have CD4 cell counts above these levels and are planning on starting therapy for the first time with a drug regimen that contains Viramune.
  
hello joemutt, thanks for joining this thread i so much appreciate it,pls read this article i posted here then check about
their daily prescriptions,my question is,is't once a day which means at the bed time and how about liver toxicity ?
1.ABC (Ziagenavir) 300mg 60 tablets 8490 THB
2.ATZ " REYATAZ 200mg 60 tablets 9750 THB
3.ATZ '' REYATAZ 300mg 30 tablets 8640 THB
4.Darunavir " PREZISTA 300mg 120 tablets 13800 THB
5.DDI " VIDEX*EC 250mg 30 tablets 2430 THB
6.DDI " VIDEX*EC 400mg 30 tablets 3750 THB
7.EFV " STROCIN 600mg 30 tablets 810 THB
8.IDV (CRIXIVAN) 180 tablets ราคา 2160 THB
9.3TC " LAMIVIR 60 tablets 570 THB
10. 3TC " LAMIVIR 30 tablets 570 THB
11.LPV/RTV " Aluvia 60 tablets 1440 THB
12.LPV/RTV " Kaletra 180 tablets 5400 THB
13.NVP " NERAVIR 60 tablets 960 THB
14.RTV " Norvia 84 tablets 3024 THB
15.SQV " Invirase 120 tablets 9360 THB
16.D4T " STAVIR 60 tablets 240 THB
17.TDF " Viread 30 tablets 1350 THB
18.AZT " ANTIVIR 100 tablets 650 THB
19.3TC+AZT " Zilavir 60 tablets 1230 THB
20.3TC+NVP+D4T" GPO vir S-30 60 tablets 990 THB
21.3TC+NVP+AZT ''GPO vir Z-250 60 tablets 1320 THB 
   
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 11, 2009, 11:47:56 pm
Another combo for you to look into as a possibility is Reyataz and Epzicom (Kivexa).

Reyataz normally has to be boosted with Norvir but with Epzicom it does not have to be boosted, so you are saving money since it's two medications (although Epzicom contains two drugs). You are also getting less toxicity without the Norvir.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 12, 2009, 12:46:32 am
Another combo for you to look into as a possibility is Reyataz and Epzicom (Kivexa).

Reyataz normally has to be boosted with Norvir but with Epzicom it does not have to be boosted, so you are saving money since it's two medications (although Epzicom contains two drugs). You are also getting less toxicity without the Norvir.
h! Inchlinblue, thanks for your contribution appreciate,anyway my worry is i don't need any thing that
will harm my liver or even leeds to keep in refrigerator cause normaly i kept my ten days doses in my hand bags
to avoid forgoting to take them.my greatest problem was this anxiety disorder that's given me though time.with
this anxiety medications (lexapro,tranxene,haldol)i'm still cann't do anything.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: joemutt on December 12, 2009, 04:32:54 am
  
hello joemutt, thanks for joining this thread i so much appreciate it,pls read this article i posted here then check about
their daily prescriptions,my question is,is't once a day which means at the bed time and how about liver toxicity ?



Hi San,
Personally  I didn't have any toxicity problems with viramune, been taking it for five years or so, if these issues do not arise in the first weeks of treatment they tend to be rare.
I take all my meds together once a day at 8.15 pm, with or without food.
Other combinations might be twice daily, I dunno that. Be well.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 12, 2009, 10:30:26 am
Here is a recent thread from somebody on Reyataz and Epzicom:

http://forums.poz.com/index.php?topic=29992.0
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 16, 2009, 11:25:59 pm


H! Esper,i've sent mail to you hoping to hear from you concerning your combo how
you're doing with it but i didn't  hear from you again ,i hope you're fine? and Inchlinblue
pls do you live in thailand?i would like to know cause i need to have friend sometime we
can chear most of our feelings regards to this hiv.thanks
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 17, 2009, 12:20:27 am

H! Esper,i've sent mail to you hoping to hear from you concerning your combo how
you're doing with it but i didn't  hear from you again ,i hope you're fine? and Inchlinblue
pls do you live in thailand?i would like to know cause i need to have friend sometime we
can chear most of our feelings regards to this hiv.thanks

I don't live in Thailand, I live in the US.

I think if you do a search for "Thailand" on here maybe you can see other forum members who are in Thailand.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: esper on December 17, 2009, 08:38:05 am
hi sanitex, thanks, am doing fine, had a couple bad days with headache but now ok....still a bit foggy in the mornings from the sustiva but its getting better each day.  I replied to your PM as well today.  seems lots of people starting up with atripla so been checking some of those threads, mostly doing ok.

how about your new regimen, sanitex, hope your able to work something out with your doc that's good for you....keep us posted. and we'll stay in touch. esper
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 24, 2009, 01:27:36 am
h! everyone
                 today i went to check for my kidney,liver,cholesterol,functions here are the result.
chol/HDL=4.2
Glucose =96normal range is 70-99
BUN  =10.1 normal range is 4-20mg/dl
Creatinine1.23=on 23/1/09 was 1 and on 13/9/09 was 1.16 then today is 1.23H normql range is 0.4-1.2
eGFR =71.17 L=normal range is 90-91
CHOL=148 =normal range is 200
TRIG=163H=normal range is 150
HDL-C=35.4L=normal range is 40
LDL(cal)80.0=normal range is 130
LDL-C=78=normal range is 130
SGOT(AST)35=normql range is 0-40
SGPT(ALT)70 H=normql range is 0-41
so my question now is ,is't too bad or is't because of TRUVADA that i changed last
time and what else should i do to get the bad good and get the high ones in other.?
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: CapeCodder on December 24, 2009, 01:28:16 pm
Hello Sanitex,

I was reading your thread about nerves and medications. It is not uncommon to have tremendous feeling of anxiety about meds. They are a constant reminder of the battle we all have with HIV.

The swimmy feelings that you write about are possibly brought on by panic attacks. I have had anxiety attacks for the last 20 years. They are not brought on by any one trigger, they just happen. I've found that when I'm alone and thinking, they tend to come more often. When I am immersed in work or other forms of entertainment, they tend to not ever manifest themselves.

You may wish to try a few things that have helped me immensely. Yoga is one that works well along with a stress management class. Deep breathing and square breathing are great as well. Any time that you have one of these attacks, its best to try to focus on something that you love to do or enjoy.

With regard to your labs: Every lab has a range of high and low as to where your numbers should be. I'm guessing that if you had your blood drawn at a different laboratory, you would see slightly different numbers. Cholesterol and Triglycerides are numbers that you can effect with lipd drugs such as Lipitor. You can also help regulate them with exercise. Being from the USA, we don't use the same numerical values that you do in Thailand (I'm assuming that you use the metric system there) so I can't really tell what the values are unless I translate each number. It doesn't seem that your liver functions are too out of whack though. I think that you should monitor the numbers over the next few visits and then talk with your doctor or a different doctor and ask him or her to interpret the numbers for you. You may find that things are better than you think. ;)
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 25, 2009, 08:59:02 pm
Hello Sanitex,

I was reading your thread about nerves and medications. It is not uncommon to have tremendous feeling of anxiety about meds. They are a constant reminder of the battle we all have with HIV.

The swimmy feelings that you write about are possibly brought on by panic attacks. I have had anxiety attacks for the last 20 years. They are not brought on by any one trigger, they just happen. I've found that when I'm alone and thinking, they tend to come more often. When I am immersed in work or other forms of entertainment, they tend to not ever manifest themselves.

You may wish to try a few things that have helped me immensely. Yoga is one that works well along with a stress management class. Deep breathing and square breathing are great as well. Any time that you have one of these attacks, its best to try to focus on something that you love to do or enjoy.

With regard to your labs: Every lab has a range of high and low as to where your numbers should be. I'm guessing that if you had your blood drawn at a different laboratory, you would see slightly different numbers. Cholesterol and Triglycerides are numbers that you can effect with lipd drugs such as Lipitor. You can also help regulate them with exercise. Being from the USA, we don't use the same numerical values that you do in Thailand (I'm assuming that you use the metric system there) so I can't really tell what the values are unless I translate each number. It doesn't seem that your liver functions are too out of whack though. I think that you should monitor the numbers over the next few visits and then talk with your doctor or a different doctor and ask him or her to interpret the numbers for you. You may find that things are better than you think. ;)
hello Cape thanks for your advice and encouragement i really understood but my main problem was the anxiety disorder which going to another
formula like inthe night i feel like i was unconscious like i'm not breathen well and my heart beat will  beat like a hamer ,but what i don't
want was i don't want to drop this combo due to it's easy to take only at bed time ,moreover no need to put inside refrigerator.but i due
 hope my anxiety came worst since i started sustiva not like before when i was only taken my anxiety meds.many combos here friends here
had recomened for me but some need to put inside the refrigerator some needs two time a day which i don't like to be taking meds during
my working time.now is like i'll try this yoga and see what will come true or wait untill there's (Isentress)in thailand then i better change to it.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: burr0108 on December 28, 2009, 06:37:05 pm
In my opinion, go on Isentress (raltegravir).  It is a 2x per day med.  However, it is incredibly potent with low side effects, if any.  I started on that + truvada.  The combo knocked my VL down from over 50000 to 728 in less than 2 weeks.

It is an integrase inhibitor, which is one of the newest classes of HIV drugs.  There is a great deal of promise with this new drug.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: Inchlingblue on December 28, 2009, 06:42:28 pm
In my opinion, go on Isentress (raltegravir).  It is a 2x per day med.  However, it is incredibly potent with low side effects, if any.  I started on that + truvada.  The combo knocked my VL down from over 50000 to 728 in less than 2 weeks.

It is an integrase inhibitor, which is one of the newest classes of HIV drugs.  There is a great deal of promise with this new drug.

I don't think it's available in Thailand yet, which is where the OP lives.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: esper on December 28, 2009, 10:58:51 pm
Correct, Inch, not here yet. my doc says may be a while for this one to come in. esper
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: John2038 on December 29, 2009, 08:37:29 am
Hi san,

sorry to read what is happening to you.

You have start Atripla very recently and I feel worth to try staying on it a bit longer if possible.

I got your symptoms 6 months after having started Atripla.

I am out of them since I tried to control my emotions, went back to the gym and added lithium (2 ml/day - do not abuse from it !) with omega 3-6-9 to my vitamins.

Controlling my emotions was a key factor. I did it by seeing people, enjoying myself and don't allowing my anxiety to even start.

I feel out of these problems now. A switch might be a solution as such symptoms can drastically reduce the quality of life and lead to bad thoughts.
But in my case, they are gone. So they can go.

If I should have taken the switch route, I would take Isentress/Truvada.
But it's a decision to be taken by your doc and you.

Best luck my friend ! You are not alone.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on December 29, 2009, 11:45:46 pm




Hi san,

sorry to read what is happening to you.

You have start Atripla very recently and I feel worth to try staying on it a bit longer if possible.

I got your symptoms 6 months after having started Atripla.

I am out of them since I tried to control my emotions, went back to the gym and added lithium (2 ml/day - do not abuse from it !) with omega 3-6-9 to my vitamins.

Controlling my emotions was a key factor. I did it by seeing people, enjoying myself and don't allowing my anxiety to even start.

I feel out of these problems now. A switch might be a solution as such symptoms can drastically reduce the quality of life and lead to bad thoughts.
But in my case, they are gone. So they can go.

If I should have taken the switch route, I would take Isentress/Truvada.
But it's a decision to be taken by your doc and you.

Best luck my friend ! You are not alone.

hello burr0108and John,thanks for you guys advice i really appreciate it,but isentress is not yet in thailand i
think i'll wait then try to control my anxiety emotions also continue the anxiety medication.
john,regard to gym i stop exercise due to this problem  sometimes i feel like maybe i will die at the
gym and whenever i step on the threadmill the indicator will show my heart beat rate is high without
even run just walk on it then i went to EST everything was ok according to my herat Doctor.now i feel
like not going to the gym  then go on diet to reduce my weight.obviously my emotions change whenever
 i go to the gym this meds is giving tough time but nothing i could do only hope one day our GOD shall
answer all of us our prayer for cure this disease . thaks san
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: thescot on January 20, 2010, 05:20:10 am
Isentress is available at Bumrungrad but its 24000thb per month. Truvada is 2500thb per month
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on January 20, 2010, 11:16:08 pm




h! thescot ,this price realy scare me that's very very expensive to start with i cann't
do that for somebody all this drug companys are thieivs.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on January 26, 2010, 02:30:26 am


h! everyone ,is't possible to take sustiva 400mg with truvada once a day to reduce the side
efect?
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: John2038 on January 26, 2010, 02:55:30 am
Hi san

you have to talk to your doc about reducing the quantity of Sustiva. Additional blood draw will be needed.
There are plenty others regimen than Isentress/Truvada. It's something you have to review with your doc.
Depending on what could be your new combo, ensure the switch is made properly.

But prior considering a switch, again, try to work on your anxiety. Take few minutes to evaluate why you are anxious today, Doing so could allows you to gain confidence.
Try to take omega 3. Studies have shows that it is as efficient as some others drugs to treat anxiety.
Try to see people. Talk every day with people. In Thailand, it's not a big deal. Go to the wat. Try to take the control of you. Try to a void eating anything in the 2h before taking your combo, and then to sleep.

You may want also to check your serotonin level and see if it is low.

You can do yoga. Do cardio at low intensity (monitoring your beat rate with a watch to stay in the 65% VO2max range). Doing so will allows you to burn fat, see people, achieve target in more of improving drastically your health and mind condition.

It's only after having really try for few weeks that I would personally consider a switch.
It's only my point of view, and only you and your doc may decide.

Be a tiger. Fight. You are the boss. Take the control. For this to work, you really have to decide.

Best Luck my friend.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on January 28, 2010, 12:03:01 am


h! john,i really appreciate your concern toward my health may the almighty God
reward you.yesterday i met my ID doc we make time discussed about my change
and he was very unhappy about my anxiety issues but he kept on encouraging me
to continuing the combo but our argumentaion end up to wait and see if my vl
goes down as before,he was thinking to put me on viramune i told him no because of
liver toxicity and not once a day regimen and he refer to isentress that one of his patient
was on that but easy to develop resistance due to time missing doses moreover the isentress is
 expencive here in thailand now.
yesterday was a happy day for me towards my test about truvada like side efect according to my
doc everything was fine no reaction notice also HBC test was negative  before he regues for
HBV HAV HCV vaccine which i took already yesterday.john thank you once again i'll pm you
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: joemutt on January 28, 2010, 03:06:24 am
San, I take truvada + viramune as a once daily regimen and I didn't have toxicity issues or rash.
I have been on viramune for quite a few years. Be Well.
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: John2038 on January 28, 2010, 02:31:41 pm
Hi san,

I am happy to read that your hepatitis tests came back all negative and that your moods have improve yesterday !

About the hepatitis A and B vaccine, be sure you will get the Twinrix (Hep A and B) and not the Energix-B (hep B only). Both need to be kept in the fridge before the injection.

You may want to add 2 others vaccines Pneumovax and Tdap (Tetanus, Diphtheria, Pertussis).

I hopes your moods will continue to improve. I know what it is. And I am fine today.
Again, omega-3 and sport are your friends, in more than taking atripla on an empty stomach !

Be Well my friend, God Bless

John
Title: Re: changing sustiva because of anxiety and to what best combo urgent
Post by: sanitex on January 29, 2010, 11:11:26 pm
About the hepatitis A and B vaccine, be sure you will get the Twinrix (Hep A and B) and not the Energix-B (hep B only). Both need to be kept in the fridge before the injection.

You may want to add 2 others vaccines Pneumovax and Tdap (Tetanus, Diphtheria, Pertussis

H! john, regards to others vaccine you mentioned i've no idea about it and my ID doc
did not mention it, maybe because we are not in the winter country off cuase thailand
is very hot to start with.HAV ,HBV, i do hope they brought it from the refrigerator as well
anyway i don't know but this is a private hospital aswell as expencive hospitalm too and i didn't
read the content what i knew was i got my hepatitis vaccine injection already.

I take truvada + viramune as a once daily regimen and I didn't have toxicity issues or rash.
I have been on viramune for quite a few years. Be Well.

H! joe, i asked my doc about once daily doses he said no it must be twice a day ,you knew
must of this doc are premature in times of hiv the only doc that will explain something
to you was DR mathana at bumunigrad ,anyway let me ses my new lab test then i'll comfirm what to do.