POZ Community Forums

Meds, Mind, Body & Benefits => Mental Health & HIV => Topic started by: tednlou2 on February 09, 2012, 12:58:55 am

Title: Cymbalta Anyone?
Post by: tednlou2 on February 09, 2012, 12:58:55 am
Does anyone have knowledge about Cymbalta?  I have a prescription for this, but haven't started it yet.  I've hesitated to start, because I was told this depression med may cause issues with the HIV regimen I've chosen to use--Truvada, Reyataz, and Norvir.  I think Norvir is the potential problem?? 

Does anyone know whether this possible interaction is really all that common?  What depression meds would go best with this regimen?  I suppose it isn't something I should even worry about now, since I'm not set to start HIV meds just yet.  And, given the rate at which many usually have to switch depression meds, I may already be looking for another by the time I do begin HAART. 

I also have questions about the Cymbalta commercials.  They mention liver problems/failure/deaths a few times in the ad.  I realize they have to say that, even if this only happened to a couple people.  But, I don't remember seeing this in ads for other depression meds.  I've tried to find info on just how common the liver issues occur in those taking Cymbalta, but haven't been able to find good info.  Cymbalta is now FDA approved for pain relief, which would be another benefit for me, since I have a lot of back problems before and after having back surgery.  They are now running ads for pain relief where they never mention depression. 
Title: Re: Cymbalta Anyone?
Post by: james3000 on February 09, 2012, 12:23:34 pm
I am on Cymbalta No-one mentioned drug interaction to me.

Someone I know was on it for PN they were on a very high dose and their vision went blurry but it does mention that in side effects and went back to normal when they stopped taking it.

I have had no side effects.
Title: Re: Cymbalta Anyone?
Post by: Miss Philicia on February 09, 2012, 01:41:32 pm
I have a prescription for this, but haven't started it yet.  I've hesitated to start, because I was told this depression med may cause issues with the HIV regimen I've chosen to use--Truvada, Reyataz, and Norvir.  I think Norvir is the potential problem??

Who told you this?
Title: Re: Cymbalta Anyone?
Post by: Rev. Moon on February 09, 2012, 03:02:01 pm
Tedderz,

Cymbalta has no documented interactions with those meds. 

I took that shit for a short while.  Hated it with a passion.  It made me totally numb and indifferent to everything around me (I even started having some serious suicidal thoughts -- can't say for sure that it was caused by the medication itself, but it is something I had not experienced before or ever since I stopped taking it).  It was my first and last experience with anti depressants. 
Title: Re: Cymbalta Anyone?
Post by: Miss Philicia on February 09, 2012, 03:15:49 pm
I took it for a while maybe six years ago, but only for 6-8 months. That was at the same time I first had high blood pressure issues so they had me go off of it to eliminate that as a cause (it wasn't the cause). However, unlike Rev. Moon, I had no side effects from it, but it also didn't help me with depression/anxiety either. I could still function sexually with it so that was fine.

All of these things have wildly different effects in every body that it's almost not worth discussing. You just take it, give it a try for a handful of months, and then it's either working or it isn't. If not move on to something else.

After Cymbalta I completely gave up on any and all anti-depressants. I think it was my sixth one I tried in as many years and nothing ever helped.
Title: Re: Cymbalta Anyone?
Post by: Buckmark on February 09, 2012, 06:12:54 pm
After Cymbalta I completely gave up on any and all anti-depressants. I think it was my sixth one I tried in as many years and nothing ever helped.

I can relate.

My experience on Cymbalta was that is made my throat feel like it was constricted, and it was definitely hard to swallow.  Very weird.  I couldn't function sexually. 

Your mileage may vary.

Almost every drug advertisement seems to warn of liver problems and "rare, but serious, side-effects".   Hard to know how much stock to put in that statement. 

Title: Re: Cymbalta Anyone?
Post by: tednlou2 on February 09, 2012, 11:11:03 pm
Who told you this?

That would be the HIV pharmacist at the HIV clinic I go to.  The same woman who told me she was sure I had a false-positive and was sure I was actually negative.  And, the same woman who made a remark that HIV is what happens when you live on the edge--or something like that.  It was hurtful. 

It sounds like the info she gave me is incorrect, from the responses.  I have no idea why I continue to listen to this woman.  She doesn't fill prescriptions like one would think.  She counsels patients on their meds.  I really need to begin looking for a private practice doc.  I stayed after getting insurance, because I felt I was now able to repay the free care I got when I didn't have insurance. 

I will just start it and see how well it works.  I'm trying to take the depression/anxiety issues more seriously and deal with them like any medical problem, instead of half-assing it.  I got a new therapist who sees many HIV poz patients.  So far, he seems great and the type who will actually work on cognitive behavior techniques.  Thanks for the replies. 

Modified:

By the way, I intend to start taking advantage of the good info in this forum.  I should have been using this forum from day one. 
Title: Re: Cymbalta Anyone?
Post by: Miss Philicia on February 09, 2012, 11:19:59 pm
I have no idea why I continue to listen to this woman.
Title: Re: Cymbalta Anyone?
Post by: BT65 on February 11, 2012, 05:20:01 am
Everyone reacts to anti-depressants differently. As Philicia said, you take it for a few months to see if it is efficacious.  If not, try something else.  They can be very helpful for persons such as yourself who are dealing head-on with depression. 

I've been taking Wellbutrin for a few years.  Not so much now because of depression, just to keep balanced.  I actually started it to quit smoking, but it didn't work for that issue.  It did seem to help me feel a bit more "up," not high, but just a bit better mood wise, so I stuck with it.

I would definitely give the Cymbalta a try and see if it helps.  Remember not to look for instant results.  Anti-depressants always take 6-8 weeks to build up and show results.  Good luck!  Glad you're in therapy now also.
Title: Re: Cymbalta Anyone?
Post by: TexasPOZ on March 12, 2012, 04:33:46 am
As far as drug interactions go, that is something to discuss with your doctor or pharmacist. I took Cymbalta for a couple of years, and it did help my depression. I was on Norvir at the time, and my doctor and pharmacist never advised me of any potential drug interactions. For me Cymbalta did nothing for my pain. But everyone is different, he may work for you. I'd say give it a try. That's the only way you'll know for sure. Good luck.
Title: Re: Cymbalta Anyone?
Post by: FD312361 on March 19, 2012, 03:08:21 pm
I am currently on Cymbalta 60 mg .  It does help with my pain.  it makes me sleepy though. and I have had no serious side affects.  I also am on Paxil, and Lorazapam.  I do believe that the statin I'm on is affecting me though.