POZ Community Forums

Meds, Mind, Body & Benefits => Research News & Studies => Topic started by: blondbeauty on August 06, 2006, 05:38:54 pm

Title: This could lead to an Anti-HIV drug resistant to mutations!
Post by: blondbeauty on August 06, 2006, 05:38:54 pm

http://webboard.aegis.org/WB/default.asp?boardid=2&action=9&read=3615&fid=9 ::)

Title: Re: This could lead to an Anti-HIV drug resistant to mutations!
Post by: J220 on August 07, 2006, 12:00:38 am

It just gives me so much hope when I read articles like this.

I wonder what kind of drugs would work to bind to PIP2, and what level of toxicity they would have?

Title: Re: This could lead to an Anti-HIV drug resistant to mutations!
Post by: J220 on August 09, 2006, 09:28:29 am

I sent the staff at HHMI an email asking for any other information they might have on this. I also read on Dr. Summer's bio that he identified a new class of compounds that inhibit a key protein involved in the transformation of HIV into its mature form. Let's hope all this leads to great things! J.

Title: Re: This could lead to an Anti-HIV drug resistant to mutations!
Post by: J220 on August 12, 2006, 03:54:59 pm

Okay I've learned that the people behind this discovery are already working on a possible deal with a pharmaceutical company to develop this. They have preliminarly identified a substance that seems to inhibit PIP2, the chemical signpost that hiv uses to attach to cellular membranes.

If this works, we are looking at a drug that would effectively block hiv from infecting cells, and not be subject to resistance issues. Fingers crossed.

J.

Title: Re: This could lead to an Anti-HIV drug resistant to mutations!
Post by: blondbeauty on August 12, 2006, 04:48:15 pm

Thats great news. But we have to be realistic. If this substance works it is still 10 years far in time.