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Author Topic: Truvada + Isentress  (Read 11162 times)

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Offline mancguy

  • Member
  • Posts: 30
Truvada + Isentress
« on: May 09, 2010, 08:07:26 am »
Hi everyone,

Planning to start meds and not sure what is the best combo for me, been reading about Truvada + Isentress, seems side effects are uncommon which really appeals to me. Just wondered if anyone on here is on them and if so how have they found them? Any informion, good and bad, would be appreciated.

mancguy
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Offline Billy B

  • Member
  • Posts: 392
Re: Truvada + Isentress
« Reply #1 on: May 09, 2010, 11:26:45 am »
Quote from: mancguy on May 09, 2010, 08:07:26 am
Hi everyone,

Planning to start meds and not sure what is the best combo for me, been reading about Truvada + Isentress, seems side effects are uncommon which really appeals to me. Just wondered if anyone on here is on them and if so how have they found them? Any informion, good and bad, would be appreciated.

mancguy

Hi Mancguy- I have been on this combo for only 7 weeks now after a very short time on Atripla. I am already undetectable,  my cd4 increased by 50 (340-390) and my platelets  went up my 6000.

The only unwanted effected I experienced was a slight rocking sensation when I would first go to bed. It resolved in about 3 days.

Oh yea, I almost forgot to mention that I can no longer eat Mexican food because of the mighty Truvada Wind.
Peace,
Billy
Logged
VL 4420 CD4 340 CD4% 24   3/15/10 Started I&T
VL  UD   CD4 340 CD4% 26.5 05/13/10
VL  UD   CD4 360 CD4% 27.1 08/3/10
VL  UD   CD4 310 CD4% 28.4 11/22/10
VL  UD   CD4 420 CD4% 27.9 02/11/11
VL  UD   CD4 370 CD4% 26.4 06/08/11
VL  UD   CD4 360 CD4% 27.7 09/23/11
VL  UD   CD4 370 CD4% 28.3 01/20/12
VL  UD   CD4 430 CD4% 28.8 05/11/12
VL  UD   CD4 370 CD4% 28.1 09/07/12
VL  UD   CD4 390 CD4% 32.3 03/14/13
VL  UD   CD4 450 CD4% 29.8 09/10/13
VL  UD   CD4 430 CD4% 31.0 04/29/14
VL  UD   CD4 520 CD4% 34.8 11/05/15
VL  UD   CD4 440 CD4% 33.5 03/10/15
VL  UD   CD4 450 CD4% 30.5 08/23/16
VL  UD   CD4 510 CD4% 34.0 07/21/20  (Biktarvy)

Offline armybent

  • Member
  • Posts: 5
Re: Truvada + Isentress
« Reply #2 on: May 09, 2010, 04:24:20 pm »
I have been positive since mid 2004.  Viral load was always low (200-2000) and CD4>500.  It was recommended to me to start on Truvada and Isentress in June of 2009.  I started then and have had no side effects to mention.  CD 4 is 710 (27%) and and viral load has been undetectable since the beginning (was 8000 before I started).  Hope this helps.

Not sure how you obtain your meds but I have found the mail order (with what ever insurance you have) is MUCH cheaper and comes right to your mailbox!

Good luck
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Offline mancguy

  • Member
  • Posts: 30
Re: Truvada + Isentress
« Reply #3 on: May 09, 2010, 04:54:21 pm »
Thank you guys, this pretty much confirms what I have already read about this combo, it will be top of my list when i meet with my consultant in two weeks time. I live in the UK so treatment is free, I just hope this combo is available here.

mancguy
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Offline Boze

  • Member
  • Posts: 477
Re: Truvada + Isentress
« Reply #4 on: May 09, 2010, 04:59:39 pm »
Mancguy,

what are you numbers? I'd also like to start this treatment but I'm not sure if the docs will allow it yet.
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==========
Aug08 - Seroconversion
Mar10 - Diagnosis; cd4 690 - VL 19,000
Apr10 - cd4 600
May10 - VL 4,500
Jun10 - started Atripla ; VL 113
Jul 10 - UD vl, CD4 590
Aug 10 - UD, CD4 810, 52%
Nov 10 - UD, CD4 980

Offline mancguy

  • Member
  • Posts: 30
Re: Truvada + Isentress
« Reply #5 on: May 09, 2010, 06:52:02 pm »
Here you go borzel

01/10 - CD4 690 – CD% 30 – VL 25K
03/10 – CD4 495 – CD% 29 – VL 55K
05/10 – CD4 380 – CD% 32 – VL 31K

mancguy
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Offline paolo10954

  • Member
  • Posts: 57
Re: Truvada + Isentress
« Reply #6 on: May 09, 2010, 11:49:31 pm »
Also started on Truvada and Isentress since April 28, 2010. I tested positive in 2003, my numbers are listed here on my profile. No side effects that I've noticed so far. After a month I go for blood work to see how it's working.

Good luck Mancguy.
Logged
jun03     hiv negative
dec03     tested positive
mar05     cd4 698  vl 23221 no meds
jul05       cd4 660  vl 2962 no meds
dec05     cd4 553  vl 5412 no meds
mar06     cd4 610  vl 3158 no meds
june06    cd4 523  vl 3924 no meds
dec06     cd4 616  vl 1236 no meds
march07  cd4 536  vl 1331 no meds
june07    cd4 486  vl   820 no meds
sept07     cd4 576  vl  380  no meds
aug08     cd4 530  vl 1725 no meds
april09    cd4 428  vl  1059 no meds
july09     cd4 511  vl   533 no meds
jan10      cd4 380  vl  1200 no meds
mar10     cd4 262  vl  2389 no meds
april28, 2010 started on Isentress and Truvada
july10     cd4 340  vl undetectable
nov10     cd4 431  vl undetectable
march11  cd4 350  vl undetectable

Offline alejandroglz

  • Member
  • Posts: 40
Re: Truvada + Isentress
« Reply #7 on: May 10, 2010, 01:44:06 pm »
Im on the same boat.....good luck with your combo!!!  :)
Logged
05/09 poz
05/09 cd4 320 vl 500,000+
06/09 cd4 560 vl 442,000
07/09 cd4 460 vl 125,000 
09/09 cd4 389 vl 140,000
10/09 cd4 349 vl 148,000
11/09 cd4 350 vl 150,000 start Isentress/Truvada (11-18-09)
12/09 cd4 509 vl undetectable! As 12-03-09 + H1N1 vaccine
04/10 cd4 560 vl und
08/10 cd4 580 vl und start Isentress 2*400ml once a day/1truvada

Uno no vino al mundo a sufrir, arriba ese animo!

Offline Miss Philicia

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  • Posts: 24,793
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Re: Truvada + Isentress
« Reply #8 on: May 10, 2010, 01:48:21 pm »
I've been on Isentress and Truvada for two years, and by far it's been the easiest combo I've ever taken (been HIV+ for ~20 years, on meds for 17).  My viral load is undetectable, cd4 count is 1380 with a 45%.
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"I’ve slept with enough men to know that I’m not gay"

Offline mancguy

  • Member
  • Posts: 30
Re: Truvada + Isentress
« Reply #9 on: May 10, 2010, 02:27:26 pm »
That's amazing Miss P, I can only dream of results like that.....congratulations!

mancguy
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Offline dist

  • Member
  • Posts: 11
  • Italian male. If you want to know more, just ask.
Re: Truvada + Isentress
« Reply #10 on: May 13, 2010, 09:55:42 am »
Dear friend, I have been on this combo for only 8 weeks and my numbers are listed below. My answer: no side effects! ;D
Logged
oct08         hiv negative
jan09         tested positive
feb09         cd4 621   vl 17000    no meds
may09        cd4 604   vl 4200     no meds
aug09         cd4 578   vl 6440     no meds
nov09         cd4 489   vl 52800   no meds
feb10          cd4 522   vl 372000  no meds
mar16, 2010 started on Isentress and Truvada
apr10           cd4 500   vl <50
may10          cd4 501   vl <50
aug10           Not Yet Available
nov10           Not Yet Available

Offline mancguy

  • Member
  • Posts: 30
Re: Truvada + Isentress
« Reply #11 on: May 13, 2010, 01:28:31 pm »
Thank you dist. How strict do you have to be with timings, do you have to stick strictly with the same time every day or is there a degree of flexibility? Also, have you noticed any interaction with other things such as alcohol (not that I drink heavily!).

mancguy
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Offline dist

  • Member
  • Posts: 11
  • Italian male. If you want to know more, just ask.
Re: Truvada + Isentress
« Reply #12 on: May 13, 2010, 03:15:27 pm »
Quote from: mancguy on May 13, 2010, 01:28:31 pm
Thank you dist. How strict do you have to be with timings, do you have to stick strictly with the same time every day or is there a degree of flexibility? Also, have you noticed any interaction with other things such as alcohol (not that I drink heavily!).

mancguy

I take Truvada (1) and Isentress (1) in the morning (8.00 a.m., taken after breakfast but i'ts not a prescription!) and Isentress (1) in the evening (8.00 p.m., before or after dinner). The doc told me that there is some flexibilty, -1.5/+1.5 h., but I'm usually very punctual. No significant interactions, but I would never suggest to take any medicine with things such as alcohol!
Recently, a very small pilot study have shown that a daily dose of 800 mg of Isentress may be safe and effective. However, the large confirmatory study is still ongoing, and everyone should wait for those results before taking Isentress once a day. We will see...
 ;)
« Last Edit: May 13, 2010, 03:20:29 pm by dist »
Logged
oct08         hiv negative
jan09         tested positive
feb09         cd4 621   vl 17000    no meds
may09        cd4 604   vl 4200     no meds
aug09         cd4 578   vl 6440     no meds
nov09         cd4 489   vl 52800   no meds
feb10          cd4 522   vl 372000  no meds
mar16, 2010 started on Isentress and Truvada
apr10           cd4 500   vl <50
may10          cd4 501   vl <50
aug10           Not Yet Available
nov10           Not Yet Available

Offline mancguy

  • Member
  • Posts: 30
Re: Truvada + Isentress
« Reply #13 on: May 13, 2010, 03:57:03 pm »
Thanks dist, much appreciated.

mancguy
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Offline decayingsinner

  • Member
  • Posts: 274
Re: Truvada + Isentress
« Reply #14 on: May 13, 2010, 07:27:36 pm »
Quote from: Billy B on May 09, 2010, 11:26:45 am


Oh yea, I almost forgot to mention that I can no longer eat Mexican food because of the mighty Truvada


Mexican food? Why is that?  I am also on Truvada, along with Sustiva.
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Offline Inchlingblue

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  • Posts: 3,117
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Re: Truvada + Isentress
« Reply #15 on: May 13, 2010, 09:39:56 pm »
Quote from: dist on May 13, 2010, 03:15:27 pm

Recently, a very small pilot study have shown that a daily dose of 800 mg of Isentress may be safe and effective. 
 ;)

I'd be curious to read about this. Do you by any chance have a link or any more information about it?
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Offline dist

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  • Posts: 11
  • Italian male. If you want to know more, just ask.
Re: Truvada + Isentress
« Reply #16 on: May 14, 2010, 01:47:04 am »
Quote from: Inchlingblue on May 13, 2010, 09:39:56 pm
I'd be curious to read about this. Do you by any chance have a link or any more information about it?
Here is a link: http://www.hivandhepatitis.com/2009icr/icaac/docs/092209_b.html
Merck is still studying Isentress once a day, but until we have the results of these new trials, I wouldn't recommend doing this.
 ;)
Logged
oct08         hiv negative
jan09         tested positive
feb09         cd4 621   vl 17000    no meds
may09        cd4 604   vl 4200     no meds
aug09         cd4 578   vl 6440     no meds
nov09         cd4 489   vl 52800   no meds
feb10          cd4 522   vl 372000  no meds
mar16, 2010 started on Isentress and Truvada
apr10           cd4 500   vl <50
may10          cd4 501   vl <50
aug10           Not Yet Available
nov10           Not Yet Available

Offline Billy B

  • Member
  • Posts: 392
Re: Truvada + Isentress
« Reply #17 on: May 14, 2010, 01:44:32 pm »
Quote from: decayingsinner on May 13, 2010, 07:27:36 pm
Mexican food? Why is that?  I am also on Truvada, along with Sustiva.

Truvada can cause gas and Mexican food always caused a problem with me anyway.
Peace,
Billy
Logged
VL 4420 CD4 340 CD4% 24   3/15/10 Started I&T
VL  UD   CD4 340 CD4% 26.5 05/13/10
VL  UD   CD4 360 CD4% 27.1 08/3/10
VL  UD   CD4 310 CD4% 28.4 11/22/10
VL  UD   CD4 420 CD4% 27.9 02/11/11
VL  UD   CD4 370 CD4% 26.4 06/08/11
VL  UD   CD4 360 CD4% 27.7 09/23/11
VL  UD   CD4 370 CD4% 28.3 01/20/12
VL  UD   CD4 430 CD4% 28.8 05/11/12
VL  UD   CD4 370 CD4% 28.1 09/07/12
VL  UD   CD4 390 CD4% 32.3 03/14/13
VL  UD   CD4 450 CD4% 29.8 09/10/13
VL  UD   CD4 430 CD4% 31.0 04/29/14
VL  UD   CD4 520 CD4% 34.8 11/05/15
VL  UD   CD4 440 CD4% 33.5 03/10/15
VL  UD   CD4 450 CD4% 30.5 08/23/16
VL  UD   CD4 510 CD4% 34.0 07/21/20  (Biktarvy)

Offline dist

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  • Posts: 11
  • Italian male. If you want to know more, just ask.
Re: Truvada + Isentress
« Reply #18 on: May 14, 2010, 09:12:23 pm »
Quote from: mancguy on May 13, 2010, 01:28:31 pm
Also, have you noticed any interaction with other things such as alcohol (not that I drink heavily!).

mancguy

Just an update for you.
Frequent Alcohol Use Might Hasten HIV Disease Progression: http://www.poz.com/articles/hiv_alcohol_cd4_761_18415.shtml
Hugs.
Logged
oct08         hiv negative
jan09         tested positive
feb09         cd4 621   vl 17000    no meds
may09        cd4 604   vl 4200     no meds
aug09         cd4 578   vl 6440     no meds
nov09         cd4 489   vl 52800   no meds
feb10          cd4 522   vl 372000  no meds
mar16, 2010 started on Isentress and Truvada
apr10           cd4 500   vl <50
may10          cd4 501   vl <50
aug10           Not Yet Available
nov10           Not Yet Available

Offline mancguy

  • Member
  • Posts: 30
Re: Truvada + Isentress
« Reply #19 on: May 15, 2010, 05:27:05 am »
thank you dist, I had already read it. I have also read that alcohol does not interfer with meds, but that alcohol may affect adherence. it all seems to relate to the quantity of alcohol drunk.

mancguy
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