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Author Topic: Breaching the blood brain barrier  (Read 3840 times)

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Offline Hoover

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  • Posts: 284
Breaching the blood brain barrier
« on: September 14, 2011, 06:29:56 pm »
Interesting article on a way to temporally open the barrier to treat the brain for many problems. HIV being one of those things that it could be beneficial to treat.
http://www.sciencenews.org/view/generic/id/334330/title/A_new_way_to_breach_the_blood-brain_barrier

You never know what is out there.

Hoover
Infection date: March 16, 2010
20/05/10 - CD4 348  VL 58,000  Lymph nodes in jaw painful!  Antioxidants started.
01/06/10 - CD4 428  VL?
24/06/10 - CD4 578  VL 9,800
13/07/10 - CD4 620  VL?
04/09/10 - CD4 648  VL?
01/11/10 - CD4 710  VL?   CD8 972
16/12/10    CD4 738  VL?  CD8  896   
02/02/11    CD4 520 (month of parasites and new lab)
14/03/11 started Truvida and Sustiva (Efavirenz)
04/07/11 CD4 686 VL 75 CD8 588  41%
10/10/11 CD4 757  45%  VL UD

Offline Ann

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  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Breaching the blood brain barrier
« Reply #1 on: September 15, 2011, 08:20:59 am »
Interesting article on a way to temporally open the barrier to treat the brain for many problems. HIV being one of those things that it could be beneficial to treat.
http://www.sciencenews.org/view/generic/id/334330/title/A_new_way_to_breach_the_blood-brain_barrier

You never know what is out there.

Hoover


Interesting indeed. I wonder if you would have to be very careful of what you ingested or breathed in during the eighteen hours the "window" is open? The article says there's still a lot more research to do on the safety of this drug, so maybe that's one of the things they still have to figure out.

Also, if you're taking this to get hiv meds into the brain, I suppose you'd have to take it all the time to prevent resistance developing in the hiv in the brain? For example, to sustiva because of the long half-life and it being trapped in the brain after the Truvada components are used up. Does that make any sense?

Colour me mystified. :o
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