LIPO REVERT

[draconcba]

Hello. I'm from Argentina and POZ since 2001. My actual treatment is Kaletra + Lamivudina + Zidovudina since 2003. My CD4 count is 600 and my viral load is >50.
I'm worried because the veins in my arms and legs are more visible (luckily my face haven't had changes yet). For this, I'm thinking to change my tratment for other without Zidovudina (AZT) but my doctor says that doing the change is not sure the lipoatrophy will revert.
Did somebody have lipo and then it dissapeared change the treatment?
I would like to hear comments about this.
Sorry for my mistakes , but my English is very basic.
I hope that you understand me. I will be waitting for yours post. Thanks a lot.

[Miss Philicia]

My answer would be a very limited, qualified "yes" -- if you catch it early enough you might see some reversal but over an extended period of time.  Lipo happens at the cellular level in terms of its damage, and as someone that has had it for a decade it's my feeling that 1) there can often be a delay in seeing the effect and 2) much of the damage is permanent, but maybe you can reverse at best one grade.

If I were you I would try switching from lamivudine and AZT to Truvada, as Truvada is viewed currently as the most lipo-friendly NRTI class medication.

So I guess what I'm saying is that even if you switched right now to Truvada you might still see lingering, delayed effects of lipo show up in your face in the next year.  It's only a possibility though, and in fact may not happen but wouldn't want you to switch to Truvada, see the lipo continue, and think it's the Truvada.  That's why I emphasized how lipo effects can seem delayed.

I hope that makes sense.

[draconcba]

Thanks Miss Phiicia for your time. The coment was very clear and I understood it. Sometimes, I think the lipo is a matter of luck 
More cuestions... 1) Do you know if I can to combine Kaletra with Truvada? - 2) Did you ever have lipo?
Thanks!
... I am waitting for other cuestions too. 

[Miss Philicia]

Thanks Miss Phiicia for your time. The coment was very clear and I understood it. Sometimes, I think the lipo is a matter of luck 
More cuestions... 1) Do you know if I can to combine Kaletra with Truvada? - 2) Did you ever have lipo?
Thanks!
... I am waitting for other cuestions too. 

1) yes, the combination of Kaletra with Truvada is used quite a bit actually.  I was on this for several years.

2) yes, I have lipo though it's not as bad as many people -- I've been on HIV treatment since 1993 so my lipo issue were most likely caused by the use of Zerit in the 90's, a medication which is not commonly prescribed now.  Whatever lipo I have I obtained before taking Kaletra/Truvada so I feel safe in describing that combo as relatively lipo free.