POZ Community Forums
Meds, Mind, Body & Benefits => Research News & Studies => Topic started by: eric48 on September 01, 2011, 05:52:08 pm
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Just got this on RSS feed:
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AIDS: discovery of a protein effective against HIV replication
(AFP) - Sept 1
STRASBOURG - Two medical teams from the Universities of Strasbourg and Marseille 2 discovered the powerful properties of a protein that prevents HIV replication, announced Thursday the Faculty of Strasbourg.
Professor Olivier Rohr and Dr. Christian Schwartz in Strasbourg, together with teachers and Eric Didier Raoult Chabrière in Marseille, have highlighted the inhibitory properties of the human protein HBPB (Human Phosphate Binding Protein) on HIV replication.
"The in vitro results show that this protein acts in a way not yet targeted by current therapies," say the scientists in a joint statement.
This protein was already known but its properties in the fight against HIV have only recently been discovered.
Moreover, this protein is also effective against strains of HIV than conventional strains resistant to antiretroviral AZT.
"This work paves the way for promising new strategies for developing therapies against HIV," said the medical team "plans to continue? Study of the mechanism? Inhibition of this protein and will soon begin testing in vivo" .
However, the widespread use of this protein may not be for several years, the time to complete all tests, first on animals and on volunteer patients.
"Now it's a question of resources," said Professor Eric Chabrière. "Right now all lights are green, the first toxicity tests have shown no side effects, but animal testing is very expensive, and humans even more."
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wait and see...
Eric
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and the original paper is here:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157455/pdf/1743-422X-8-352.pdf
eric
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"This work paves the way for promising new strategies for developing therapies against HIV,".....
"the widespread use of this protein may not be for several years."....
"Now it's a question of resources," said Professor Eric Chabrière.
Boilerplate announcements - love em or leave em?
Nothing against this one per se.
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hoopla
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To be ready in 2060...
:P
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i just love how every few days someone throws in a topic and the thread goes on forever :-)
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i just love how every few days someone throws in a topic and the thread goes on forever :-)
Hey! :o this one is pretty short so far. :D
I mean this is only the 5th reply. LOL
at least we know it's not going to go on as long as the 49 yrs it's going to take to perfect this newest "cure du jour" lolz it'll be a zombie thread long before we reach that date. :D
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"It's a question of resources."
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To be ready in 2060...
:P
Magnifique. Most, if not all, of us will be fabulous corpses by the time that this materializes.
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But there will have already been that patented milk shake cure by 2030. (Medicinal tasting and only 2 flavors -Mokka Banana or Berry.)
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A bunch of hubaloo.
The research forum is quite exhausting. All these "discoveries." Its hard not to get bitter. Yes I know, progress.
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The research forum is quite exhausting. All these "discoveries." Its hard not to get bitter. Yes I know, progress.
I kinda enjoy the research forum. ;)
I understand that none of this stuff is anywhere close to helping me; but for all those newbies screaming where is my cure? why no cure after only 30 yrs when so many other things haven't been cured either? ::) Then that forum is a good place to point and say, see the scientists are working their asses off. It's just a hard damned bug to cure and if you're waiting for "the cure", you've got a long freaking wait. So get on the stick and stick to those antiretrovirals because those are the only thing you've got to combat the HIV.
it's good to see that the scientists are trying so many various methods, and that they are learning so much about the human body at such a cellular level. Personally though, I'm just not going to waste my time and hope on a cure though, because that forum shows how fantastically hard it's going to be to find a "cure". However that forum also shows that we haven't been forgotten and they are still trying to find us that cure. ;)
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A bunch of hubaloo.
The research forum is quite exhausting. All these "discoveries." Its hard not to get bitter. Yes I know, progress.
Bitter? Really? Each advancement in the treatment of this disease has prolonged and provided a better quality of life than was ever anticipated. As a middle aged man who was infected when I was pert near a child, I am grateful for every stride that is achieved.
I'm also grateful that I've always chosen to look for that silver lining in this hideous disease and fought to maintain my existence. Perhaps it's a mindset?
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I agree with you Leatherman and Wolfter.
I was just noticing, that I DID notice how boilerplate this PR announcement is. Which means I've finally seen enough of them to get to that critical awareness that people with a long experience of HIV already have.
I had the good fortune (ironically put) to seroconvert so recently that I haven't found a personal need to invest much time/attention to learning about research into HIV and HIV treatment, and learning about the history of the battle for treatment. I just gleaned what I know from living through the whole history of the epidemic, but I wasn't positive, and never a treatment activist for example.
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I do not discount the progress that has been made regarding research of this disease. Nor do I think that it is hopeless and we are all destined to be doomed. I think I was just trying to convey that there is Soooo much written about this discovery, and that discovery. It gets overwhelming. Especially when the majority of "discoveries" do not lead to tangible results (at least immediately tangible).
AND how each discovery is posted on this research forum like its the pandora! the breakthrough that we have all been waiting for.
Thats all. I'm very gratefull for the advances and hope for more. I am actually quite optimistic about the future of this disease.
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Oh come on bugsy -- you mean you don't google "HIV + Cure" every 3 hours, every day like the rest of us? 8)
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I havent googled that in over 2 years I think. ::)
Not my job to worry about and the news will travel like lightening, rest assured.
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I like reading here because I find scientific research interesting. And sometimes it's good to raise your spirit, so I like it when people post news here. Science moving forward (or trying to) is always good.
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I like reading about research as well, and have posted in this forum before on research I have found interesting or may be usefull to people.
I think the thing that bothered me about this post was the: BREAKING NEWS headline of the thread. It makes it sound like it is more than what it is..if that makes sense.
I stopped googling HIV Cure awhile ago. It is much easier on my psyche to try and learn to be comfortable with my positive status and be gratefull when and if a cure does come than to ride the google cure roller coaster. I think that is something that every newly positive person goes through (or at least its common).
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I've never googled HIV + Cure my entire life.
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Ive never googled those specific words either. I have googled "hiv" on google news. I havent done that in quite awhile. I figure if its important enough I would read it on aidsbeacon or poz.co
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I've never googled HIV + Cure my entire life.
you and I had HIV before Google was even a gleam in the internet's eye. :D Hell, we had HIV before there was even a medication for it. It's no wonder that you or I haven't googled "HIV cure" because we have personal knowledge of the epidemic and have had competent doctors that would have told us the moment a cure was discovered.
However, I'm not surprised that someone newly diagnosed, who probably hasn't given HIV much of a thought will google up info about HIV to see if there's a cure. Most people don't give a rip about some disease or illness that they don't have themselves, therefore don't know much about a disease until they get it and need to know. Looking for info about HIV is also why many of those people end up here ;)
One of the huge misconceptions out there is that the treatments today are damned near a cure. I'm sure many people wonder how HIV can be a big deal if the problem is solved with a pill a day. We often here people on here (who don't really understand the science and the medicine) who can't believe that there's not a cure after 30 long years.
Google returns about 18,400,000 results (0.07 seconds) for "HIV cure" so it's obviously a much-talked about subject. I would even venture to say that that result has gone up recently because nearly the whole first page of google returns IS about the cure! the "cure" of the Berlin Patient. (of course, I prefer to call it the "eradication of his HIV" not cure). So since there has been a "cure", it's no wonder that people would google up "HIV cure".
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Actually I had internet capabilities within 12 months of diagnosis, and IIRC WebSearch was used as a search engine followed soon by Altavista. Such was life in NYC at the time.
And before you try and split hairs Bivens-style just don't (http://en.wikipedia.org/wiki/Google_(verb)).
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When there is a real, verifiable, tangible CURE, I figure the news will find me before I even consider looking for it.
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I've never googled HIV + Cure my entire life.
Me neither. I've always figured when a real, practical cure comes along, we're going to know about it pretty quickly, so why bother?
When there is a real, verifiable, tangible CURE, I figure the news will find me before I even consider looking for it.
'zactly.
I found this place a few weeks after my diagnosis by searching for "hiv support". Been a member ever since. I didn't even have my own computer back then - my ex-husband gave me a key to his house and a quick introduction to turning on a computer and getting on the internet.
Luckily, he had a great ex-office laser printer that used very little ink and he allowed me to print off as many pages as I wanted as long as I used my own paper. I would go there while he was at work and print off reams of information to read at home. I used to have a complete collection of the Lessons here.
To be honest, the only articles in this forum I usually bother with really reading are ones about new drugs in trials. Anything else I read here I only read from a moderator point of view - trying to herd cats in other words. ;D
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Dear Ann, so do I, and also bother to read those related to trials comparing combos and those about long term secondary effects. But I must confess I read ones about vaccine research from time to time too. To be updated I read POZ news, Google news and these forums. Googleing times are gone with the winds of facts. They're steps: recently diagnosed, starting meds, getting used to meds, being married to meds, being a pill box with a human body at a series equipment. Each one of these stimulates different needs for information. Oh my god, I am getting old!
BTW, Ann, I love your avatar!!!
Hugs!
F :-)