Jacques:
"Non-personalized HIV immunotherapies are unable to raise cytotoxic T lymphocytes against HIV antigens, fail to induce T cell memory, and, most importantly, do not provide antiviral protection against the patient's own particular virus," said Jean-Pierre Routy, M.D., of McGill University Health Center and Royal Victoria Hospital, the principle investigator and sponsor of the study. "A personalized immunotherapy addresses these issues because it is able to capture private viral mutations, providing a matched, complete immune response for each individual HIV patient. This approach may overcome the weaknesses of other available therapies and therefore could result in a better chance of success for HIV treatment."
LINK to complete article: http://findarticles.com/p/articles/mi_m0EIN/is_2007_Feb_9/ai_n27143927
All I know about this study (held in Montreal) is that phase I results will be presented in Mexico Hiv conference next week and that phase II is already recruiting.
Jacques
bimazek:
this seems a bit similar to some other treatment i posted about which is good in that the persons own hiv is disabled sliced up so to speak and the parts, peptides and proteins are forming a kind of super vaccine
if you saw the TV movie John Adams about the 2nd usa president that was kind of the state of ART of vaccines in 1700s i posted about that on my bimazek research or somewhere else
i just looked at the press release it is 2007
a few other points
according to one of the TOP hiv experts at Univ of California -- the body everyones body is great at suppressing the virus that was in body 6 months ago -- he said this in a lecture --- that if the body only had to deal with the version of virus in a few months it completely is able to deal with it, but the virus constantly changes its outer shell or its shape or something
basically this is the familiar mutation issue but on a micro level
in other words there can be millions of mutations that occur every day to the virus
ONLY a few actually are big enough to cause RESISTANCE to an HIV med or class of meds
so basically it is the old story of the swarm of viruses constantly mutating micro mutation everyday
every few weeks the virus escapes the immune system and the body has to build defense and this constant process is very destructive over time
so personalized may help in some way
i never understood why they dont just get all the versions together and make a vaccine out of a million different versions
there must be some UPPER limit to the versions or maybe it is like shapes of cars and models of cars and cars with dents there are infinite number of car bodies if you include the little dents that get in a car
even though there are only 300k different car bodies produced in history