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Author Topic: Drunken feeling on Atripla  (Read 5470 times)

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Offline conwaygay

  • Member
  • Posts: 9
Drunken feeling on Atripla
« on: December 11, 2012, 02:54:30 pm »
I'm on day 5 of Atripla.  The first few nights I had vivid dreams, but haven't had any since.  I do find that the slightest things will wake me, though, and it's really hard to fall back asleep once I wake.  This doesn't bother me much, at least yet.
What bothers me is that I've felt really disoriented and drunken for the majority of the day every day since taking it (I take it around 1030pm).
I'm a nursing student and I work, so feeling like this makes it really hard to be productive and really hard to concentrate.
I've read people say they feel hung over in the mornings, but I feel flat out drunk until just a few hours before taking the meds again.
Does this side effect generally dissipate after a few weeks?
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Offline WindySkies

  • Member
  • Posts: 113
  • Tested + 10/11/12
Re: Drunken feeling on Atripla
« Reply #1 on: December 11, 2012, 03:05:24 pm »
What about switching to something else that doesn't have those side effects?
Logged
10/11/2012 Journey Started
10/17/2012 First Labs: VL=57,645  CD4+=730  37%
10/31/2012 Started Complera
11/30/2012 Labs: VL=80  CD4+=929 40%
12/24/2012 Started Stribild

Undetectable since 1/15/13 CD4+= Over 1,400 and 49%

Offline conwaygay

  • Member
  • Posts: 9
Re: Drunken feeling on Atripla
« Reply #2 on: December 11, 2012, 03:11:59 pm »
Quote from: WindySkies on December 11, 2012, 03:05:24 pm
What about switching to something else that doesn't have those side effects?

I'm going to give Atripla a month, at least. I want my meds to be consistent and taken often to avoid resistance.
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Offline WindySkies

  • Member
  • Posts: 113
  • Tested + 10/11/12
Re: Drunken feeling on Atripla
« Reply #3 on: December 11, 2012, 03:52:57 pm »
Quote from: conwaygay on December 11, 2012, 03:11:59 pm
I'm going to give Atripla a month, at least. I want my meds to be consistent and taken often to avoid resistance.

If you stay in the same family of drugs you shouldn't have an issue jumping back and forth. Complera and Stribild would fall into the same family as Atripla.  I'm switching from Complera to Stribild and was told I can always go back to Complera at any point if need be.

I would discuss it with your doctor at the very least. It's bad enough having to live with HIV, why take on further unnecessary stuff to deal with.
Logged
10/11/2012 Journey Started
10/17/2012 First Labs: VL=57,645  CD4+=730  37%
10/31/2012 Started Complera
11/30/2012 Labs: VL=80  CD4+=929 40%
12/24/2012 Started Stribild

Undetectable since 1/15/13 CD4+= Over 1,400 and 49%

Offline Miss Philicia

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  • Posts: 24,793
  • celebrity poster, faker & poser
Re: Drunken feeling on Atripla
« Reply #4 on: December 11, 2012, 03:58:02 pm »
Quote from: WindySkies on December 11, 2012, 03:52:57 pm
If you stay in the same family of drugs you shouldn't have an issue jumping back and forth. Complera and Stribild would fall into the same family as Atripla.  I'm switching from Complera to Stribild and was told I can always go back to Complera at any point if need be.

I would discuss it with your doctor at the very least. It's bad enough having to live with HIV, why take on further unnecessary stuff to deal with.

You should be able to change regimens from one class to another without there being an issue as well. Where did you come up with this theory about needing to stay in one class?
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"I’ve slept with enough men to know that I’m not gay"

Offline NY2011

  • Member
  • Posts: 173
Re: Drunken feeling on Atripla
« Reply #5 on: December 11, 2012, 04:42:02 pm »
Give it some time. The drunky feeling may subside.  It comes back every night for me if I'm still up for about an hour after I take it. It did make me feel disoriented for the first week or so.  I remember someone saying that it doesn't go away..you'll just get used to it.  That ended up not being true.  I feel fine during the day.  It'll be a year on Jan 27th for me. 

What you should watch for is a rash on the the seventh or eighth day.  That was from hell.
Logged
10/26/2011 - SEROCONVERSION (fever+rash, 104 degrees F)
10/31/2011 - CD4= 154  VL>500,000 
10/31/2011 - started on Truvada+Prezista+Norvir
12/14/2011 - CD4= 750 VL=6412 (45%)
01/27/2012 - switched to Atripla
04/23/2012 - CD4=1,221 VL= 140  (47%)
06/22/2012 - CD4=1,224 VL= ud    (49%)
12/18/2012 - CD4=1,031 VL= ud    (51%)
09/16/2013 - CD4=1,151 VL= ud   (49%)
03/26/2014 - CD4=1,050 VL= ud
11/25/2014 - CD4=1,335 VL= ud
12/01/2015 - CD4=1,115 VL= ud (55%)
11/22/2016 - CD4=1,071 VL= ud (52%)
06/01/2017 - CD4=1,014 VL= ud (53%)
switched to Biktarvy in 2018
04/23/2019 - CD4=1,072 VL= ud (52%)
01/15/2020 - CD4=  925  VL= ud (50%)

Offline vaguesbleues

  • Member
  • Posts: 97
Re: Drunken feeling on Atripla
« Reply #6 on: December 11, 2012, 05:46:21 pm »
Quote from: WindySkies on December 11, 2012, 03:52:57 pm
If you stay in the same family of drugs you shouldn't have an issue jumping back and forth. Complera and Stribild would fall into the same family as Atripla.  I'm switching from Complera to Stribild and was told I can always go back to Complera at any point if need be.

While Complera and Atripla both contain two nucleoside reverse transcriptase inhibitors + a non-nucleoside reverse transcriptase inhibitor, Stribild is different.  Stribild contains two nucleoside reverse transcriptase inhibitors + an integrase inhibitor (with a boosting agent).  Stribild = Single-Tablet Regimen Integrase-Based by gILD (Gilead), while the other two single-tablet regimens are based around NNRTIs.
Logged
3/10/11 - HIV-
4/26/11 - Inconclusive WB
5/19/11 - HIV+, VL < 50, T-Cell 747 (30%)
6/13/11 - VL 345, T-Cell 841 (30%)
8/23/11 - VL 50,100, T-Cell 1155 (19%) - CMV
9/18/11 - Started Atripla
11/7/11 - VL 489, T-Cell 881 (31%)
2/8/12 - VL Undetectable!, T-Cell 772 (34%)
8/8/12 - VL UD, T-Cell 1070 (42%)
11/5/12 - VL UD, T-Cell 1174 (35%)
3/18/13 - VL UD, T-Cell 972 (28%)
10/4/13 - VL UD, T-Cell 1025 (34%)
2/9/14 - VL UD
7/31/14 - VL UD
1/29/15 - VL UD, T-Cell 1027 (32%)
9/15/15 - VL UD
10/21/16 - VL UD, T-cell 765 (39%)
4/28/17 - VL 29
8/17 - started Genvoya
10/27/17 - VL UD, T-cell 880 (35%)
3/30/18 - VL UD
9/28/18 - VL UD, T-cell 980 (34%)
4/19/19 - VL UD
10/18/19 - VL UD
10/22/20 - VL UD, T-cell 1005 (35%)

Offline brenner

  • Member
  • Posts: 93
Re: Drunken feeling on Atripla
« Reply #7 on: December 12, 2012, 09:57:24 am »
It does get better.  I know that drunk, out of body feeling that atripla gave me.  It goes away with time. Its almost 2 years for me, and i cannot say anything bad about it...good luck.
If it persists, talk to ur doctor and you can come up with another regiment together.
Logged
Feb 23. 2011  poz diagnosed
Feb 28.  cd4 257, vl 262400, %21
Mar 14.  start Atripla
May 18.  cd4 639, vl 690, %33
Aug 19.  cd4 583, vl 60, %38
Nov 18.  cd4 450, vl UD, %38
2012
Feb.19   cd4 649, vl UD, %35
Jun 08.  cd4 524, vl UD, %34
Sep 16.  cd4 567, vl UD, %35
Dec 02.  cd4 592, vl UD, %35
2013
Mar 10.  cd4 688, vl UD, %35

Offline bufguy

  • Member
  • Posts: 214
Re: Drunken feeling on Atripla
« Reply #8 on: December 17, 2012, 01:27:59 pm »
I've been on Atripla for 4-1/2 years now. The first 10 days were bad...anxious, achy, jittery, just feeling unwell. After that the side effects quickly subsided.
Today I have absolutely no problems. I can even take it after a full meal...no side effects. Give it a chance....plus I have been consistently undetectable and my CD4 is over 1200.
Logged
5/29/08 confirmed HIV+
6/23/08 Vl 47500  CD4 511/29% CD8 .60
start atripla
8/1/08 Vl 130  CD4 667/31% CD8 .70
9/18/08 Vl un  CD4 not tested
12/19/08 Vl un CD4 723/32% CD8 .80
4/3/09 Vl un CD4 615/36% CD8  .98
8/7/09 vl un CD4 689/35% CD8 .9
12/11/09 vl un CD4 712/38% CD8 .89
4/9/10 vl un CD4 796/39% CD8 1.0
8/20/10 vl un CD4 787/38% CD8 1.0
4/6/10 vl un CD4 865/35% CD8 .9
8/16/10 vl un CD4 924/37% CD8 1.0
12/23/10 vl un CD4 1006/35% CD8 .9
5/2/10 vl un CD4 1040/39% CD8 .9
8/7/13 vl un CD4 840/39% CD8 .
11/29/18 vl un CD4 1080/39% CD8  .86

Offline Ithappens

  • Member
  • Posts: 7
Re: Drunken feeling on Atripla
« Reply #9 on: December 17, 2012, 07:56:53 pm »
It does get better.  I've been on it for almost 4 years and  the first few days on Atripla i felt high as a kite and completely disoriented if i woke up at night to use the bathroom.  I'd have to hold on to the walls to find my way back to my bed.
Logged
4/2009 Negative
6/24/09 ER with 104 degree temp
July-Nov 09 constantly had a cold and was tired, late Nov i asked to be tested
11/30/09 Tested positive and my Dr had the results confirmed before he told me
12/30/09 Appt with ID MD
1/28/10 cd4: 382 VL:72226
2/11/10 Started Atripla
4/10 cd4: 530 VL: UD
8/10 cd4: 551 VL: UD
11/10 cd4: 430 VL: UD
3/11 "                     "
9/11 cd4: 628 VL: UD
2/12 cd4: 638 VL: 103
7/12 cd4: 644 VL: UD 35%
1/13 cd4: 665 VL: UD 36%
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