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Author Topic: Second Generation of NNRTI's poised for treatment naive studies  (Read 3779 times)

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Offline J.R.E.

  • Member
  • Posts: 8,207
  • Positive since 1985, joined forums 12/03
Second Generation of NNRTI's poised for treatment naive studies
« on: January 10, 2008, 04:10:24 pm »
Logged
Current Meds ; Viramune / Epzicom Eliquis, Diltiazem. Pravastatin 80mg, Ezetimibe. UPDATED 2/18/24
 Tested positive in 1985,.. In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started on  HAART on October 24th, 2003.

 UPDATED: As of April, 2nd 2024,Viral load Undetectable.
CD 4 @593 /  CD4 % @ 18 %

Lymphocytes,total-3305 (within range)

cd4/cd8 ratio -0.31

cd8 %-57

72 YEARS YOUNG

Offline Patrick

  • Member
  • Posts: 86
  • Where the determination is, the way can be found.
Re: Second Generation of NNRTI's poised for treatment naive studies
« Reply #1 on: January 13, 2008, 03:08:10 pm »
Good news here too.  I believe there are four new drugs mentioned in here that will be hitting the market between 2008-2012 that all offer better barriers to resistence than Sustiva and Viramune, but less side-effects.  Another step forward, and more options for all of us.

With progress like this, I feel that in 10 years, drug regimens for HIV will have advanced to the point where mutation around them will be so difficult as to be almost a non-issue with persons who adhere well to the regimens.  Side-effects will be minimal or none.  Hopefully having HIV can eventually be reduced to simply having to take some pills in the morning and then that's it.  No side-effects (short or long term) and little to no viral resistance to the regimen.

I think this will be the reality of cutting edge HIV therapy around the year 2020.  Articles like this show that we continue to move in that direction.
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Seroconversion - late October 07
11/14/07 - CD4 190   VL >750,000
11/14/07 - Started Truvada & Kaletra
12/5/07 - CD4 851     VL 710
2/19/08 - CD4 604     VL Undetectable
5/8/08 -   CD4 829     VL Undetectable
8/12/08 - CD4 915     VL 80 (blip)
11/11/08 - CD4 967    VL Undetectable

Offline tucker

  • Member
  • Posts: 35
Re: Second Generation of NNRTI's poised for treatment naive studies
« Reply #2 on: January 21, 2008, 01:51:21 pm »
that would be wonderful, and it is what I am hoping for, myself.  I am still treatment naive... so starting meds has me kind of nervous.  Really hoping to keep that at bay for another couple of years...  I am amazed and grateful for the amount of resources being devoted to combatting this bug.
Logged
confirmed diagnosis 10.1.07
10/07  cd4 504 vl 40,000
1/08  cd4 524 vl 73,000
4/08  cd4 484 vl 48,060
6/02/08 started Truvada, Reyetaz, Norvir
7/08 cd4 605! vl 400
9/08 cd4 713 vl 175

k103 mutation :(
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