Welcome, Guest. Please login or register.
March 28, 2024, 08:05:57 am

Login with username, password and session length


Members
Stats
  • Total Posts: 772945
  • Total Topics: 66310
  • Online Today: 375
  • Online Ever: 5484
  • (June 18, 2021, 11:15:29 pm)
Users Online
Users: 0
Guests: 360
Total: 360

Welcome


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Do I Have HIV?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Anyone on Aptivus?  (Read 4165 times)

0 Members and 1 Guest are viewing this topic.

Offline jkinatl2

  • Member
  • Posts: 6,007
  • Doo. Dah. Dipp-ity.
Anyone on Aptivus?
« on: July 06, 2006, 09:27:11 pm »
http://news.yahoo.com/s/po/20060706/co_po/aidsdruglabelwarnsofcranialbleeding

<<The strict "black-box" warning on the label of the HIV drug Aptivus is being changed to warn of potential fatal bleeding within the brain.

Aptivus, a protease inhibitor which blocks an enzyme which HIV needs to make more copies of itself, has been linked to 14 reports of intracranial hemorrhaging.

Eight of those patients died. There are 6,840 HIV patients taking the medication as part of antiretroviral therapy in clinical trials.

Aptivus already has a "black box" warning, the strictest a prescription drug can bear, over concerns the medication could lead to potentially serious liver problems, especially in patients with liver disease.>>


Holy crap.
"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

Welcome Thread

Offline Matty the Damned

  • Member
  • Posts: 12,277
  • Antipodean in every sense of the word
Re: Anyone on Aptivus?
« Reply #1 on: July 06, 2006, 09:48:03 pm »
I read this in the Clinical Trials forum. I agree, babe -- Holy Crap!!!!

MtD
(Who has enough trouble with his brain and liver)

Offline allanq

  • Member
  • Posts: 713
Re: Anyone on Aptivus?
« Reply #2 on: July 06, 2006, 09:58:02 pm »
I was on Aptivus (tipranavir) for 2.5 years. No major problems, but I just switched to Previzta (TMC114), which was approved two weeks ago. Previzta supposedly has fewer side effects than other protease inhibitors, but who knows what will surface a few months or a year from now. At least the Previzta requires only half as much Norvir as Aptivus (2 pills a day, instead of 4). Norvir really screws around with your cholesterol and triglycerides and is also a major cause of diarrhea.

Allan

Offline jkinatl2

  • Member
  • Posts: 6,007
  • Doo. Dah. Dipp-ity.
Re: Anyone on Aptivus?
« Reply #3 on: July 06, 2006, 10:04:23 pm »
I totally know what you mean about Norvir. Even the little amount needed to boost Reyataz was enough to send me into a prolonged case of the nasties. Let's just say that I have great empathy for Joe (killfolie)'s use of rubber bands.

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

Welcome Thread

Offline MSPspud

  • Member
  • Posts: 614
  • Joined Mar 2005 - Formerly UofMurbs
Re: Anyone on Aptivus?
« Reply #4 on: July 07, 2006, 11:03:35 am »
Now that TMC114 is approved I can't imagine why anyone would continue with Aptivus, since it has better activity against resistance with less effects.  Aptivus sounds wretched!!

 


Terms of Membership for these forums
 

© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.