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Meds, Mind, Body & Benefits => Research News & Studies => Topic started by: Andy Velez on July 23, 2007, 08:52:46 am

Title: Atripla v combivir/efavirenz study reported at IAS in Australia
Post by: Andy Velez on July 23, 2007, 08:52:46 am

Dear All,

FYI, I received this e mail this morning:

Hello,

 

A three-year head-to-head study comparing AtriplaTM (efavirenz 600 mg/ emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg) components to a regimen of Combivir and efavirenz was presented today at the International AIDS Conference on HIV Pathogenesis, Treatment and Prevention in Sydney, Australia.

 

The study (Study 934) compares the safety and efficacy of a once-daily treatment regimen of Truvada® (emtricitabine and tenofovir disoproxil fumarate) and Sustiva® (efavirenz), to a twice-daily regimen of Combivir® (zidovudine/ lamivudine) with Sustiva once daily.  After 144 weeks of treatment, the regimen of Truvada/Sustiva was associated with significantly greater virologic suppression compared to a Combivir-based regimen, and also caused greater increases in CD4 cell counts and fewer side effects that resulted in study discontinuation.  (Truvada and Sustiva are now available in the United States as the fixed-dose tablet, Atripla.)

 

Full details are contained in the attached press release.  Please let me know if you would like any additional information about the study.

 

Thanks you,

 

James

---
James Loduca
Public Affairs
Gilead Sciences, Inc.
333 Lakeside Drive
Foster City, CA   94404
p: (650) 522-5908 l f: (650) 522-5953
jloduca@gilead.com l www.gilead.com
 

Title: Re: Atripla v combivir/efavirenz study reported at IAS in Australia
Post by: J220 on July 23, 2007, 09:35:13 am

Excellent, thanks for posting this. J.

Title: Re: Atripla v combivir/efavirenz study reported at IAS in Australia
Post by: emeraldize on July 23, 2007, 10:45:00 am

Thanks Andy!

Title: Re: Atripla v combivir/efavirenz study reported at IAS in Australia
Post by: vivyt on July 29, 2007, 04:27:43 pm

I am taking Atripla and have responded very well to it. I was diagnosed 2 months ago and have been on it about that long so I can't really talk about the long term effects. I can tell you that my count has gone up and I feel MUCH better.