My viral load has remained suppressed for more than 18 months on darunavir/norvir monotherapy and, germane to this thread, within a few days I felt a lot less wiped out than when I was on combination therapy.
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Zohar,
You still don't understand. You are not on a monotherapy if you are takiing duraunavir + norvir, as that is two drugs. You are still on a combo, just not on a triple or more therapy.
Joe
Zohar:
--- Quote from: killfoile on April 26, 2013, 06:32:20 pm ---Zohar,
You still don't understand. You are not on a monotherapy if you are takiing duraunavir + norvir, as that is two drugs. You are still on a combo, just not on a triple or more therapy.
Joe
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I'm sorry, but you are misinformed. As the headline and the article show (cited again below), darunavir and norvir prescribed together are known as 'monotherapy' because, in spite of being a two drug regimen, the norvir at the dose its used here, is given specifically as a darunavir booster, rather than for its antirviral activity.
''Boosted darunavir monotherapy works well in two studies'
--- Quote from: Matts on April 26, 2013, 05:37:58 pm ---Prezista Monotherapy- thats interesting, please keep us updated :)
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Hi, As I said above I've been on it for over 18 months now and have consistently remained undetectable. Truvada just didn't agree with me and not only would I feel shattered but friends would comment on how worn out I looked. Literally, within around 48 hours of dropping Truvada I felt so much better -like a constant hangover had lifted. The fatigue I experience now tends to be episodic, whereas before it was ever-present. So boosted darunavir monotherapy definitely seems to be the most suitable option for me.
Miss Philicia:
12 hours ago you sure were singing from a different hymnal.
Zohar:
--- Quote from: Miss Philicia on April 26, 2013, 07:33:10 pm ---12 hours ago you sure were singing from a different hymnal.
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To clarify, when I was on combination therapy my energy levels were far, far lower than when I switched to monotherapy. I do still get tired now, but it's less constant and more manageable.