FDA approved kidney drug reduces chronic inflammation & complements HAART

[Cosmicdancer]

A drug called Sevelamer, used to treat people receiving kidney dialysis "significantly diminishes the levels of bacteria that escape from the gut and reduces health complications in non-human primates infected with the simian form of HIV".  Blocking bacteria from leaving the intestine reduces the chronic immune activation and inflammation, and improves health outcomes.  Researchers noted that the benefits are greater if people start treatment sooner after infection.  Clinical trials in humans are underway. 

Breakthrough in HIV/AIDS research gives hope for improved drug therapy
Date: May 16, 2014
Source: University of Pittsburgh Schools of the Health Sciences

Summary: The first direct proof of a long-suspected cause of multiple HIV-related health complications was recently obtained by a team of researchers. The finding supports complementary therapies to antiretroviral drugs to significantly slow HIV progression. The study found that a drug commonly given to patients receiving kidney dialysis significantly diminishes the levels of bacteria that escape from the gut and reduces health complications in non-human primates infected with the simian form of HIV.

The first direct proof of a long-suspected cause of multiple HIV-related health complications was recently obtained by a team led by the University of Pittsburgh Center for Vaccine Research (CVR). The finding supports complementary therapies to antiretroviral drugs to significantly slow HIV progression.

The study, which will be published in the June issue of the Journal of Clinical Investigation and is available online, found that a drug commonly given to patients receiving kidney dialysis significantly diminishes the levels of bacteria that escape from the gut and reduces health complications in non-human primates infected with the simian form of HIV. The study was funded by the National Institutes of Health (NIH).

"We now have direct evidence of a major culprit in poor outcomes for some HIV-infected people, which is an important breakthrough in the fight against AIDS," said Ivona Pandrea, M.D., Ph.D., professor of pathology at Pitt's CVR. "Researchers and doctors can now better test potential therapies to slow or stop a key cause of death and heart disease in people with HIV."

(to read the full article, click the link below)

http://www.sciencedaily.com/releases/2014/05/140516203222.htm

[tryingtostay]

I wonder if it's offered as a stand alone therapy drug?