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Author Topic: AMEN to the Hard-Ons... WARNING... Strong language here...  (Read 40333 times)

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Offline GSOgymrat

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Re: !!!
« Reply #50 on: November 03, 2010, 01:32:35 pm »
definitely a bully statement!!!

Obviously I should have stated my opinion a better way, since you took what I said as being bullied which was not my intent. I apologize for my tone but my opinion regarding doctor shopping still stands. I'm glad to see you are working with your providers and hope your condition improves.

Offline MarcoPoz

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #51 on: November 03, 2010, 01:44:30 pm »
Thank you sweetheart and at least you are supportive in your way not like those bullies that think that are not bullies but are really bullies.  You know who you are for the evidence is on this thread. 

I have talked to a psychiatrics, male and much older, and he was very supportive about my interests in getting testosterone therapy and told me of all the treatment out there and how they work and how effective they are.  I did not felt marginalized, or ignored nor belittled.  He was understanding and warned me that I need a doctor to check on my health for there are dangers of testosterone therapy. 

I have told my primary physician to talk to the pharmacy so to get more information and understand the treatment options.  The pharmacists wanted to talk to my doctor for she felt that the doctor did not understand all the options in getting testosterone therapy. Therefore, next week when I see my primary physician, in that she will be better informed and have information and support to give me.

Goof for you for attempting to get to the bottom of this and enlisting the help of physicians and pharmacists.  I hope it all comes to a good outcome soon for you.

Because of being a life-long athlete, I sometimes jump to caution very quickly when it comes to self-care with testosterone issues.  I see that is NOT the case with you and hope you take my advice in the brotherly way it was offered.  Hang in there--let's hope for more vim and vigor!

Offline red_Dragon888

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Re: !!!
« Reply #52 on: November 03, 2010, 09:57:54 pm »
Obviously I should have stated my opinion a better way, since you took what I said as being bullied which was not my intent. I apologize for my tone but my opinion regarding doctor shopping still stands. I'm glad to see you are working with your providers and hope your condition improves.
I accept your apology.
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Offline Jeff G

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Re: !!!
« Reply #53 on: November 03, 2010, 10:06:00 pm »
I accept your apology.

That's mighty big of you , I hope this doesn't offend you cuz I know you have been on a diet forever  ;)
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #54 on: November 03, 2010, 10:28:38 pm »
So anyone who gives you thoughts that are different than yours are now bullies??  Really?  So, just why did you post this if you only wanted people to validate your thoughts?  The fact remains that you have a testosterone result in the normal range (upper end, if I remember correctly) -- this is a fact that you supplied.  So, do what you will but stop asking for advice that you clearly do not want.

Also, your overuse (and gross misuse) of the bully term is maddening -- given all the kids who are now dead due to actual bullying, perhaps you should rethink tossing this term around simply because others are forcing you to look at the other side of an issue.  That is not bullying it is called helping.
hummmm....   I guess I was a bit over sensitive, and maybe I was not expecting strongly contrary or opposing opinions in a matter that is close to my heart.  After all, the subject of the slow castration, in the literal and figurative sense, of my libido is happening.  As for the term “bully,” I did not mean to touch on the current events of hate crimes.  Nevertheless, I would have not brought this subject up if I knew I would have this reaction.  I guess I was looking for support in the wrong place.  I won’t make that mistake again,  So for now on I will keep my topics on “two subjects: the weather and everybody's health. 'Fine day' and 'how do you do?' And not just let myself go on things in general.”


Burnt once, hence twice shy...

I thought this was a group of supportive people, but it is just a group of people.  My mistake…  


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Offline red_Dragon888

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Re: !!!
« Reply #55 on: November 03, 2010, 10:30:30 pm »
That's mighty big of you , I hope this doesn't offend you cuz I know you have been on a diet forever  ;)
lol...  thanks for that.  It came just in time.
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #56 on: November 05, 2010, 11:45:52 am »
I maybe the one that has to apologies for now I know that my negative energy may have been directed toward people that in no way should have been belittled.  I am thinking that my caffeine intake has added to my anxiety and I put that negative feelings to others and my doctor.  Sorry about that.  Of course I will listen to my doctor advice but I must stress that I have zero sexual drive in a time when I should have an "out of control" sexual drive.  In a way I do not miss it for I would just be a slut and fuck till I drop.  Now I feel nothing, but I hope if I did find someone that is worthy to have a strong relationship with, that then it would be good to have sex again. 

Well later and again sorry for my negative and anxious thoughts.
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #57 on: November 06, 2010, 09:17:10 am »
Dragon,

Competitive athlete here---testosterone gels or injections aren't a long term answer here unless you have a specialist working with you on the issue of low testosterone.  The bump you get from artificial T sure will make you feel better for the short term, but it begins to effect the body's natural production of testosterone--then you crash harder and feel MUCH worse than you do right now.  

I'm no angel--so I try not to tell adults what to do--but you are looking at some fairly negative consequences by playing lab rat with your hormone levels.  If you DO inject---PLEASE learn how to inject cleanly and safely.  If you were my brother--I'd tell you to put down the 'roid dream for a minute and try:

Exercise!  Get into a progressively more intense work out plan.  You'll look better, feel better and have more and stronger erections.

Exercise outdoors--no matter the weather--get your ass outside and do something physical.

Don't eat crap.  Processed--sugar-loaded-fat dripping-garbage slows everything down and limps your Willy.  Eat like a caveman while working out.  You'll feel better.

See a nutritionist and sports trainer to set up a diet and workout plan.

Check yourself in the mirror after a couple of weekes--you'll feel sexier, look sexier, exude more confidence, have better erections and you may even get laid  ;D

Noting in a salve, bottle or needle can have this effect over the long term without a myriad of other nasty side effects.   My advice---wanna feel more like a man----do more man-like things.
What do you men "man-like thngs?"  ???
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #58 on: November 10, 2010, 05:25:35 pm »
OK, I lied.  I finally went back to my primary doc today to either get the testosterone therapy or switch to a doc that will work with me on this issue.  To my surprise, my doc was more open to let me try the gel, my least favorite option and monitor my vitals for, at worst case, prostrate cancer and other side effects.  I can only assume that my doc talked to the pharmacy and got the information she needed to change her mind and I am glad she did.  Now I will received the gel tomorrow and see if it is effective in bringing back my libido to its full potential. 

red...
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Offline Jeff G

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #59 on: November 10, 2010, 05:55:00 pm »
Doctor shopper !
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Offline GSOgymrat

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #60 on: November 10, 2010, 06:11:03 pm »
Please keep us apprised of any UPdates.

Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #61 on: November 17, 2010, 10:25:37 am »
Doctor shopper !
coward..if you can't stand up for yourself, why bother.
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #62 on: November 17, 2010, 10:42:55 am »
Well, I drop the doc anyway cause I feel her interest are not compatible with my interest so bye, bye doc.  I hope the new doc is more open minded  and will help me and discuss my situation more.  The old doc made me feel that she was doing research on my condition and that she want me to stay within her criteria’s, whether it help or hurt my HIV problem seemed not to be the main focus.  It was just to keep me in her study using whatever her paper dictates.  Sorry Bitch, I ain't nobodies Ginny Pig except my own. 

Currently, the testosterone gel has lifted my spirits, both mentally and physically, and I am feeling that old "MOJO" come back. Mojo is libido for you kids out there, and not to be confused with "MoJo JoJo" the evil character on "Powerpuff Girls." I still have not achieve the rock hard erection yet, that may take time for the body to adjust, but if necessary I may resort to the injections to make that goal work.  I have been having sex and I have top some, but I want a stronger erection that last longer than a minute.
http://www.youtube.com/watch?feature=player_embedded&v=I3ba3lnFHik

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Granny60

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #63 on: November 17, 2010, 12:05:55 pm »
Now the doc wants me to see a mental health professional as if talking it out will bring it back or make me feel better. My sexual drive had a mind of its own and drove me to Sexual Fucking Paradise, there and back again. What, am I suppose to get use to this Low Ebb Shit and become a Fucking Hermit.  NO FUCKING WAY!!!

modified for emphasis

 Yeah,  Hubbies urologist wanted to send him to a shrink.  said that low testosterone causes depression and he wouldn't give testosterone because of prior cancer. WTF?  The shrink ain't gonna raise the testosterone or the flag pole.  If talking to it would have fixed it, we would have had some lovely chats a long time back.  ::)

Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #64 on: November 23, 2010, 03:22:35 pm »
Yeah,  Hubbies urologist wanted to send him to a shrink.  said that low testosterone causes depression and he wouldn't give testosterone because of prior cancer. WTF?  The shrink ain't gonna raise the testosterone or the flag pole.  If talking to it would have fixed it, we would have had some lovely chats a long time back.  ::)
sounds like bullshit to me.  either they are too lazy to give the shots or the don't give a fuck how men feels when their sex life is slipping away.  find another doctor...
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Offline Miss Philicia

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #65 on: November 23, 2010, 03:45:37 pm »
How old are you?
"I’ve slept with enough men to know that I’m not gay"

Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #66 on: December 06, 2010, 02:43:29 pm »
I feel for “Testosterone Shot” but he was going a bit over board.  I guess he is the type when push comes to shove, he is going to shove harder and harder.  However, with that said, those same members who take it upon themselves to take a subject and make it into their own comedy show are always the same.  They don’t seem to think that they maybe hurting others feelings or attacking people in away that they won’t get in trouble for.  They attack without seeming to attack.  Yeah, they have found a way to attack and come out the victim.  So I guess it is part of this community that they can act like bullies and push others around.  I wish it wasn’t so, but there is nothing new under this sun and that is life on this planet earth. 

I hope that Testosterone Shot is given a cooling off period.
« Last Edit: December 06, 2010, 02:53:26 pm by red_Dragon888 »
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Offline Denver Toad

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #67 on: December 06, 2010, 02:57:24 pm »
Dragon, all the bullying commentary and perpetual  whining makes you sound like a perpetual and professional victim. Drop the attitude and you'll be far better received.
« Last Edit: December 06, 2010, 03:06:26 pm by Denver Toad »
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #68 on: December 06, 2010, 03:04:45 pm »
Dragon, all the bullying commentary and perpetual  hining makes you sound like a perpetual and professional victim. Drop the attitude and you'll be far better received.
sticks and stones baby...  lol
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #69 on: December 06, 2010, 03:34:51 pm »
Dragon, all the bullying commentary and perpetual  whining makes you sound like a perpetual and professional victim. Drop the attitude and you'll be far better received.
another bully
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #70 on: December 06, 2010, 03:35:26 pm »
For those of you (men)  who have facebook, type TESTOSTERONE REPLACEMENT THERAPY EDUCATION in the search box and join the group. Daily postings on testosterone research and other important topics for men.
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Offline daysleeper

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #71 on: December 07, 2010, 11:12:18 pm »
My most recent T lab result: 377. I'm 38. Normal, or low for my age?

Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #72 on: December 09, 2010, 10:47:45 am »
My most recent T lab result: 377. I'm 38. Normal, or low for my age?
You would have to do some research on what is normal for that age but here is an article I have just received today and it may give you some insight. 

Editorial
Testosterone Deficiency and Replacement in Older Men


William J. Bremner, M.D., Ph.D.


N Engl J Med 2010; 363:189-191July 8, 2010




    It is now clear that men have gradual declines in average serum testosterone levels as they age. These decreases begin by middle age and continue into old age.1,2 Although the decreases are substantial in many men, they are quite variable. Some men, even in old age, maintain serum testosterone levels similar to those of healthy young men.


    Many of the physical and behavioral changes that occur in men as they age are similar to those that occur in younger men with hypogonadism. These changes include decreases in muscle mass, strength, bone mass, and sexual function and increases in body fat, fatigue, and depressed mood. It is therefore reasonable to ask whether testosterone deficiency could be causing some of the adverse physical and behavioral changes of aging and whether these could be improved with the administration of testosterone.


    The diagnosis of testosterone deficiency in older men is complicated by the fact that many older men (more than 20% in some studies) have testosterone levels that are lower than the normal range in younger men. In addition, the clinical presentation of male hypogonadism is nonspecific and overlaps with that of other illnesses and with the aging process itself. Therefore, it is frequently unclear in caring for individual older patients whether the diagnosis of hypogonadism is appropriate and whether testosterone administration might be helpful or might instead cause adverse effects.


    Two articles in this issue of the Journal address these important issues.3,4 Wu et al.3 report on a population survey of 3369 men, 40 to 79 years of age, in eight European centers. Results of the survey with respect to subjects' general, sexual, physical, and psychological health were compared with morning measurements of total and free testosterone levels in the subjects' serum. Among many symptoms surveyed, three sexual symptoms (poor morning erection, low sexual desire, and erectile dysfunction) and three general symptoms (inability to perform vigorous activity, depression, and fatigue) were associated with low testosterone levels. Further analysis showed that the presence of at least three sexual symptoms in a man with a total testosterone level of less than 11 nmol per liter (3.2 ng per milliliter) could be used to define late-onset hypogonadism. This conclusion was validated in a second data set in the same study. These conclusions are a valuable addition to earlier research, as well as to society guidelines,5,6 which have also proposed the combination of symptoms and low testosterone levels to establish the diagnosis of late-onset hypogonadism. The difficulty with using symptoms alone to define late-onset hypogonadism was highlighted by the finding that more than 25% of men with normal testosterone levels had similar sexual symptoms.


    Among older men with testosterone deficiency, can we replace testosterone in an effective and safe manner? Many studies involving limited numbers of men have shown that the administration of testosterone results in improved muscle mass and strength, increased bone mass, and other positive effects.7 None of the studies have been of sufficient size or duration to adequately address potential risks, such as the risk of prostate disease. The study by Basaria et al.4 was designed to assess whether leg-muscle strength in older men with severe limitations in mobility was increased as a result of testosterone administration. Community-dwelling men 65 years of age or older with a testosterone level of 100 to 350 ng per deciliter (3.5 to 12.1 nmol per liter) were randomly assigned to receive a transdermal gel containing testosterone (to achieve testosterone levels of 500 to 1000 ng per deciliter [17.4 to 34.7 nmol per liter]) or placebo. The 209 participants had a high prevalence of hypertension, diabetes, hyperlipidemia, and obesity. During the experimental phase, the testosterone group showed greater leg and arm strength than did the placebo group but also had higher rates of cardiovascular adverse effects. The excess of cardiovascular events in the testosterone group led the data and safety monitoring board to recommend early termination of the study. Of initial concern was the fact that 10 of the 106 men receiving testosterone had adverse cardiac events, as compared with 1 of the 103 men receiving placebo. Further investigation at the request of the data and safety monitoring board showed excesses of “cardiovascular-related” events in the testosterone group. These results are surprising, since many studies with cumulative numbers of subjects greater than those reported here have not detected substantial increases in cardiovascular risk during testosterone administration (including many studies in which subjects achieved the same or higher serum testosterone levels, some for longer periods of time).8 As the authors state, there is a clear possibility that their results are due to chance.


    Many readers may disagree with the decision of the data and safety monitoring board to terminate the study early. Results of studies terminated early may differ from those of larger, longer-term studies. Also, readers will speculate that the higher rates of adverse events in the testosterone group may have been due to the fact that the two groups of men had different baseline characteristics, with a higher rate of hyperlipidemia and statin use and of hypertension in the testosterone group before the experimental interventions. To me, the decision of the data and safety monitoring board seems reasonable. For whatever reason, there were higher rates of cardiovascular disease in the group of men who were receiving testosterone in this study than in their counterparts who were receiving placebo.


    Although this result sounds a note of caution in general concerning testosterone administration in older men, it certainly should not deter investigators from proceeding with additional, larger studies of testosterone administration in well-characterized groups of older men to more clearly outline benefits and risks. Similarly, it should not prevent clinicians from prescribing testosterone replacement for well-established late-onset hypogonadism, although it should provide some new caution about the administration of testosterone in older men who have an extensive history of cardiovascular disease and immobility.


    Ultimately, we will need large, carefully designed trials of testosterone administration, perhaps along the lines of the Women's Health Initiative. Such trials should include a sufficient number of subjects to allow the assessment of key clinical outcomes, such as bone-fracture rates, muscle strength, and avoidance of falls, and an assessment of the role of testosterone replacement in the prevention of psychiatric disease, as well as the risks for prostate, cardiovascular, and other adverse outcomes. The numbers of older men receiving testosterone are large and increasing. We owe it to our patients and their families as well as to our physician colleagues to have much better data and guidelines for the administration of this critical hormone.


    Disclosure forms provided by the author are available with the full text of this article at NEJM.org.
    Source Information


    From the Department of Medicine, University of Washington, Seattle.
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #73 on: December 09, 2010, 10:49:12 am »
NATAP http://natap.org/
_______________________________________________

Adverse Events Associated with Testosterone Administration - publication pdf attached


"In this study of older men with low testosterone levels and limitations in mobility, random assignment to daily application of a testosterone gel, as compared with a placebo gel, was associated with a greater frequency of adverse events, particularly cardiovascular, respiratory, and dermatologic events"


Shehzad Basaria, M.D., Andrea D. Coviello, M.D., Thomas G. Travison, Ph.D., Thomas W. Storer, Ph.D., Wildon R. Farwell, M.D., M.P.H., Alan M. Jette, Ph.D., Richard Eder, B.A., Sharon Tennstedt, Ph.D., Jagadish Ulloor, Ph.D., Anqi Zhang, Ph.D., Karen Choong, M.D., Kishore M. Lakshman, M.D., Norman A. Mazer, M.D., Ph.D., Renee Miciek, M.S., Joanne Krasnoff, Ph.D., Ayan Elmi, B.A., Philip E. Knapp, M.D., Brad Brooks, B.S., Erica Appleman, M.A., Sheetal Aggarwal, B.S., C.C.R.P., Geeta Bhasin, B.A., Leif Hede-Brierley, Ashmeet Bhatia, M.B., B.S., Lauren Collins, R.N.P., Nathan LeBrasseur, Ph.D., Louis D. Fiore, M.D., and Shalender Bhasin, M.D.


N Engl J Med 2010; 363:109-122July 8, 2010






ABSTRACT


Background


Testosterone supplementation has been shown to increase muscle mass and strength in healthy older men. The safety and efficacy of testosterone treatment in older men who have limitations in mobility have not been studied.


Methods


Community-dwelling men, 65 years of age or older, with limitations in mobility and a total serum testosterone level of 100 to 350 ng per deciliter (3.5 to 12.1 nmol per liter) or a free serum testosterone level of less than 50 pg per milliliter (173 pmol per liter) were randomly assigned to receive placebo gel or testosterone gel, to be applied daily for 6 months. Adverse events were categorized with the use of the Medical Dictionary for Regulatory Activities classification. The data and safety monitoring board recommended that the trial be discontinued early because there was a significantly higher rate of adverse cardiovascular events in the testosterone group than in the placebo group.


Results


A total of 209 men (mean age, 74 years) were enrolled at the time the trial was terminated. At baseline, there was a high prevalence of hypertension, diabetes, hyperlipidemia, and obesity among the participants. During the course of the study, the testosterone group had higher rates of cardiac, respiratory, and dermatologic events than did the placebo group. A total of 23 subjects in the testosterone group, as compared with 5 in the placebo group, had cardiovascular-related adverse events. The relative risk of a cardiovascular-related adverse event remained constant throughout the 6-month treatment period. As compared with the placebo group, the testosterone group had significantly greater improvements in leg-press and chest-press strength and in stair climbing while carrying a load.


Conclusions


In this population of older men with limitations in mobility and a high prevalence of chronic disease, the application of a testosterone gel was associated with an increased risk of cardiovascular adverse events. The small size of the trial and the unique population prevent broader inferences from being made about the safety of testosterone therapy.


Limited mobility is a common geriatric condition that is a predictor of disability, poor quality of life, and death.1-7 In men, an age-related decline in the serum testosterone concentration is associated with reduced muscle mass and lower-extremity strength, limitations in physical function, and poor mobility. 8-13 Testosterone supplementation increases muscle mass and strength and leg power, all of which are important determinants of mobility.14-21 Previous trials of testosterone supplementation have been conducted primarily among healthy older men. The safety and efficacy of testosterone treatment in improving muscle performance and physical function in older men with limitations in mobility have not been studied.


The Testosterone in Older Men with Mobility Limitations (TOM) trial was a placebo-controlled, randomized trial that was designed to determine the effects of testosterone administration on lower-extremity strength and physical function in older men with limitations in mobility and low serum levels of total or free testosterone.22 In December 2009, a data and safety monitoring board, established by the National Institute on Aging, determined that the incidence of adverse cardiovascular events in the TOM trial was significantly higher in the testosterone group than in the placebo group. The members of the data and safety monitoring board therefore recommended that enrollment and administration of the study medications be discontinued. We report here the adverse events associated with testosterone therapy in the TOM trial. The effects of testosterone therapy on efficacy outcomes are reported briefly.




Adverse Events


In the testosterone group, as compared with the placebo group, there were significantly more adverse events and significantly more subjects who reported one or more adverse events (Table 2 in the Supplementary Appendix). Twice as many men in the testosterone group as in the placebo group were referred for medical evaluation owing to an adverse event. Men who were assigned to testosterone also reported a greater number of serious adverse events and a greater number of adverse events that were considered to be life-threatening, although the differences between the groups were not significant (Table 3 in the Supplementary Appendix).


Significantly more men in the testosterone group than in the placebo group had adverse events in three MedDRA categories: cardiac disorders; respiratory, thoracic, and mediastinal disorders; and skin and subcutaneous tissue disorders (Table 2 in the Supplementary Appendix). Of particular concern to the data and safety monitoring board was the greater number of subjects with adverse cardiac events in the testosterone group than in the placebo group (10 vs. 1) (Table 3). In accordance with the recommendation of the data and safety monitoring board, two additional analyses of cardiovascular events were performed (Table 3Table 3Subjects with One or More Cardiovascular-Related Adverse Events.). A total of 23 men in the testosterone group and 5 in the placebo group had cardiovascular-related events; 7 men in the testosterone group and 1 in the placebo group had atherosclerosis-related events.


The risk of a cardiovascular-related adverse event remained significantly greater among men in the testosterone group than among men in the placebo group after adjustment for age group, body-mass index, smoking status, high-density lipoprotein cholesterol level, and presence or absence of diabetes, hyperlipidemia, and hypertension (Table 4Risk of Adverse Events with Testosterone Therapy, According to Category.). In time-to-event analyses, the relative risk of a cardiovascular-related event remained constant throughout the 24-week intervention period (Figure 1Time-to-Event Analysis of Adverse Events, According to Body System.). There were few adverse events during the 3-month observation phase after the end of the intervention period.


There was no evidence of a significant relationship between potential risk factors and cardiovascular-related events in time-to-event analyses (Figure 2 in the Supplementary Appendix). Men with testosterone levels in the highest quartile during the intervention period, as compared with all other subjects, were at elevated risk for cardiovascular-related events (hazard ratio, 2.4; P=0.05). Among subjects who were randomly assigned to the testosterone group, testosterone levels during the intervention period were available for 81 subjects. Cardiovascular-related events were reported in 4 of 14 subjects with testosterone levels higher than 1000 ng per deciliter during the treatment period, by 5 of 21 with levels of 500 to 1000 ng per deciliter, and by 7 of 46 subjects with levels of less than 500 ng per deciliter.


One man in the testosterone group had a hematocrit that was higher than 54%, and one reported having received a diagnosis of prostate cancer. One man in the placebo group underwent transurethral resection of the prostate.




Discussion


In this study of older men with low testosterone levels and limitations in mobility, random assignment to daily application of a testosterone gel, as compared with a placebo gel, was associated with a greater frequency of adverse events, particularly cardiovascular, respiratory, and dermatologic events. The divergence between the groups in the incidence of cardiovascular adverse events was maintained over the 6-month intervention period and did not diminish during the 3-month observation phase that followed the intervention period. The increased cardiovascular risk in the testosterone group was seen with all three definitions of cardiovascular events, and the increase persisted after adjustment for baseline risk factors. The increased risk was also evident in sensitivity analyses adjusted for baseline mobility status and Short Physical Performance Battery score and in sensitivity analyses performed after the exclusion of subjects whose eligibility deviated from the planned criteria. The pattern of adverse cardiovascular events associated with testosterone therapy was considered by the data and safety monitoring board to be of sufficient concern to warrant termination of the trial.


The generalizability of our data about the safety of testosterone therapy is limited by several factors. First, cardiovascular events were not a planned primary or secondary outcome, and therefore, a structured evaluation of cardiovascular events was not performed, a factor that may have influenced the ascertainment of events. Most of the cardiovascular-related events were verified from medical records or by direct examination. Second, the sample, although larger than those in most previous trials, was small, and the number of adverse events was small. The results of individual small trials may not be confirmed in large trials,28 and trials that have been stopped early tend to overestimate treatment differences. Third, the clinical characteristics of our study population differ from those of most other populations in which testosterone therapy has been administered in a clinical setting or as part of a clinical trial. Men who were younger than 65 years of age and men with severe hypogonadism were excluded from the trial. Participants had substantial limitations in mobility and a high prevalence of chronic conditions, including preexisting heart disease, obesity, diabetes, and hypertension. Frail elderly men with limitations in mobility are more likely to have clinical and subclinical cardiovascular disease than are those who do not have limitations in mobility.29,30


Previous studies provide very limited data to either reinforce or contradict the findings in this study with respect to the effects of testosterone therapy in older men with limited mobility. Meta-analyses of previous trials of testosterone therapy have not shown significant increases in cardiovascular risk with testosterone therapy, although nonsignificant increases have been noted among participants of all ages,31-33 as well as among older men.31,33 The trials in these meta-analyses were limited by inadequate methods of ascertaining adverse events or the poor quality of data on adverse events, by the small numbers of events or the small numbers of older participants, or by intervention periods that were shorter than the 6-month intervention in this trial. Some epidemiologic studies have shown that low testosterone levels are an independent risk factor for death from cardiovascular causes and from all causes.34-37 However, differences between the effects of endogenous hormones and those of pharmacologic hormonal therapy, as well as differences in the duration of exposure to testosterone, could contribute to the apparent discrepancies between these epidemiologic data and the results of our trial.


It is not likely that the adverse cardiovascular events seen in the TOM trial are a consequence of an unusual protocol for testosterone administration (Table 4 in the Supplementary Appendix). The upper limit of the testosterone threshold used for inclusion in the trial is not dissimilar to that used in most other trials.16-19,38-47 The testosterone doses in this trial may have been higher than those that are typically used in clinical practice48 and were higher than the doses used in some previous trials17,18,39-42 but were similar to those in other trials.16,21,43-46 The average testosterone concentrations during the intervention period among men in our testosterone group were in the middle of the normal range for young men; these levels were higher than those in some testosterone trials17,18,39-42 but did not differ from levels reported in other trials.16,19,21,43-46


The cardiovascular adverse events reported in the TOM trial were diverse and may have variable clinical importance. The lack of a consistent pattern in these events and the small number of overall events suggest the possibility that the differences detected between the two trial groups may have been due to chance alone. The results of several separate analyses were consistent with the initial observation of a significant difference, but these analyses were not entirely independent of one another. In interpreting these findings, it is essential to recognize the role that chance may have played in the outcomes we observed.


The diversity of cardiac adverse events also renders the events less susceptible to a single mechanistic explanation. Testosterone causes salt and water retention,49-51 particularly in older men,14 and this could contribute to edema, hypertension, and congestive heart failure, although there are some trials in which testosterone has been administered in men with congestive heart failure.39,40 Testosterone and associated increases in estradiol may promote inflammation, coagulation, and platelet aggregation.52 The use of anabolic steroids has been associated with left ventricular hypertrophy and systolic and diastolic dysfunction.53,54 Changes in plasma lipid levels would not account for the rapid divergence in rates of cardiovascular adverse events.


Testosterone therapy was associated with significant improvements in leg-press and chest-press strength and in stair-climbing power with a load. Inferences regarding efficacy are limited because of the attenuation of statistical power owing to the early termination of the trial.


In conclusion, we evaluated the effect of testosterone supplementation in men 65 years of age or older who had limitations in mobility and low serum levels of total or free testosterone. The trial was stopped before enrollment had been completed because of an incidence of adverse cardiovascular events that was higher in the testosterone group than in the placebo group. However, caution is warranted in interpreting this finding, because of the small numbers of events and because of limitations with respect to the ascertainment of adverse events. Caution is also warranted in extrapolating these findings to other doses and formulations of testosterone or to other populations, particularly young men who have hypogonadism without cardiovascular disease or limitations in mobility.


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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #74 on: December 09, 2010, 10:50:06 am »
--------------------------------------------------------------------------------

NATAP http://natap.org/
_______________________________________________

Sex Still Important to Older Men


MedPage Today
Published: December 07, 2010


Action Points 


    * Explain that interest and involvement in sex remain strong among many men as they age -- even into their 90s.




    * Note that among men who reported not being sexually active, almost half said their main reason was because of physical problems or limitations.


Interest and involvement in sex remain strong among many men as they age -- even into their 90s, an Australian cohort study found.


Among 2,783 men ages 75 to 95, 48.8% (95% CI 47 to 50.6) felt that sex was still at least somewhat important in their life, according to Zoë Hyde, MPH, of the University of Western Australia in Crawley, and colleagues.


And almost one-third of men in this age group (30.8%, 95% CI 29.1 to 32.5) reported having sex at least once within the previous year, the researchers reported in the Dec. 7 issue of Annals of Internal Medicine.


Data are inadequate on the attitudes and behaviors surrounding sex among older men, as well as the physical and social factors that influence their sexual activity.


So Hyde and colleagues undertook a population-based study of community-dwelling men, interviewing them at three time points between 1996 and 2009 about their health and sexual activity.


Testosterone levels also were measured at each visit.


Three-quarters were married or in a long-term relationship, and 85.9% reported having had some sexual activity during their lifetime.


Most had had sex only with women, and most had only one partner.


Among the 857 men who continued to be sexually active, more than half said they were satisfied with the frequency of sex, while 43% said they would like to have sex more often.


Participation in sex declined over time, from 39.6% (95% CI 36.7 to 42.4) of men 75 to 79 having had sex at least once during the previous year, to 11% (95% CI 4.2 to 17.8) among those in their 90s having had sex that often.


A similar pattern was seen for men who continued to consider sex important to them, which decreased from 59% (95% CI 56.2 to 61.8) of men in their 70s to 20.9% of those over 90 (95% CI, 12.5 to 29.3).


Among men who reported not being sexually active, almost half said their main reason was because of physical problems or limitations.


Other reasons included lack of interest and physical problems for their partner.


On multivariate cross-sectional analysis, decreased odds of sexual activity were associated with these factors:


    * Increasing age, OR 0.90 (95% CI 0.88 to 0.93, P<0.001)
    * Partner's lack of interest, OR 0.10 (95% CI 0.08 to 0.14, P<0.001)
    * Partner's physical limitations, OR 0.43 (95% CI 0.30 to 0.60, P<0.001)
    * Osteoporosis, OR 0.60 (95% CI 0.42 to 0.85, P=0.004)
    * Prostate cancer, OR 0.38 (95% CI 0.29 to 0.51, P<0.001)
    * Diabetes, OR 0.69 (95% CI 0.55 to 0.88, P=0.002)
    * Antidepressant use, OR 0.52 (95% CI 0.36 to 0.77, P=0.001)
    * Beta-blocker use, OR 0.68 (95% CI 0.55 to 0.85, P=0.001)


A longitudinal analysis had similar results, and also determined that each standard deviation increase in free testosterone was associated with a 20% increased likelihood of having had sex during the previous year.


The researchers noted that while prostate cancer was associated with decreased likelihood of having had sex -- probably because of hormone-based treatments -- prostatectomy was not, "perhaps reflecting improvements in surgical technique."


They observed that the link with diabetes was not surprising, because of the well-recognized detrimental effects of diabetes on sexual functioning.


The association with antidepressant use could reflect either impaired libido relating to depression or the adverse effects of the drugs, they explained, and the association with beta-blocker use most likely related to side effects of the drugs.


The researchers also noted that "an important and novel finding" was the longitudinal association between free testosterone and sexual activity, although they acknowledged that it's unclear whether testosterone therapy would be of benefit, particularly because the most common reason for sexual inactivity was the men's health problems.


Nonetheless, the study suggested that "a substantial proportion of older men may have unmet sexual needs," the authors wrote.


The study's limitations included the possibility of recall and response bias and survivorship effects over time.


They concluded that further research could help elucidate possible ways of improving sexual function in men of this age group.


The study was supported by the National Health and Medical Research Council of Australia and the MBF Foundation of Australia.




Primary source: Annals of Internal Medicine
Source reference:
Hyde Z, et al "Prevalence of sexual activity and associated factors in men aged 75 to 95 years: a cohort study" Ann Intern Med 2010; 153: 693-702.
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong Testosterone language here...
« Reply #75 on: December 09, 2010, 11:24:12 am »
Just a special note:  The gel seems to make a difference, but I am still trying to get the shots. 
http://www.youtube.com/watch?feature=player_embedded&v=I3ba3lnFHik

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Offline AlanBama

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #76 on: December 09, 2010, 11:35:40 am »
I have been on testosterone replacement therapy for quite awhile now.   I get an injection every 2 weeks.
It definitely helps with my energy levels, and sex drive as well, I suppose.  However, I (age 54) must still use some 'assistance' to function well.   Caverject works well for me, and I have used it as an e.d. med for years now.   Perhaps you need to see a urologist about some e.d. meds (levitra, cialis, etc).   I'm not sure what your age is....

I don't think anyone here is trying to 'bully' you, just giving sound advice.   Testosterone therapy is not something to take lightly.   If the numbers indicate that you don't need it, then you probably don't.

Alan

PS -- we were ALL energizer bunnies , in our day....LOL
"Remember my sentimental friend that a heart is not judged by how much you love, but by how much you are loved by others." - The Wizard of Oz

Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #77 on: December 09, 2010, 07:24:12 pm »
I have been on testosterone replacement therapy for quite awhile now.   I get an injection every 2 weeks.
It definitely helps with my energy levels, and sex drive as well, I suppose.  However, I (age 54) must still use some 'assistance' to function well.   Caverject works well for me, and I have used it as an e.d. med for years now.   Perhaps you need to see a urologist about some e.d. meds (levitra, cialis, etc).   I'm not sure what your age is....

I don't think anyone here is trying to 'bully' you, just giving sound advice.   Testosterone therapy is not something to take lightly.   If the numbers indicate that you don't need it, then you probably don't.

Alan

PS -- we were ALL energizer bunnies , in our day....LOL
Thanks for the information.  As for the bullies, they could have been helpful, but instead they were negaitive and spiteful.  Some worst than others.  You just have to read the thread, “Testosterone Shot,” to see what I mean.  They egged him on and he lost his cool.  I hope the management keeps watch of those who partook in those shameful actions.  And btw, I am 51.  There are those who, like yourself, were helpful and I am thankful for that.

red_Dragon888
« Last Edit: December 09, 2010, 07:28:56 pm by red_Dragon888 »
http://www.youtube.com/watch?feature=player_embedded&v=I3ba3lnFHik

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #78 on: December 10, 2010, 02:29:52 pm »
Testosterone Deficiency and Replacement in Older Men - Editorial
 
(Very interesting article)
  
William J. Bremner, M.D., Ph.D.
From the Department of Medicine, University of Washington, Seattle.
 
N Engl J Med 2010; 363:189-191July 8, 2010
 
It is now clear that men have gradual declines in average serum testosterone levels as they age. These decreases begin by middle age and continue into old age.1,2 Although the decreases are substantial in many men, they are quite variable. Some men, even in old age, maintain serum testosterone levels similar to those of healthy young men.
 
Many of the physical and behavioral changes that occur in men as they age are similar to those that occur in younger men with hypogonadism. These changes include decreases in muscle mass, strength, bone mass, and sexual function and increases in body fat, fatigue, and depressed mood. It is therefore reasonable to ask whether testosterone deficiency could be causing some of the adverse physical and behavioral changes of aging and whether these could be improved with the administration of testosterone.
 
The diagnosis of testosterone deficiency in older men is complicated by the fact that many older men (more than 20% in some studies) have testosterone levels that are lower than the normal range in younger men. In addition, the clinical presentation of male hypogonadism is nonspecific and overlaps with that of other illnesses and with the aging process itself. Therefore, it is frequently unclear in caring for individual older patients whether the diagnosis of hypogonadism is appropriate and whether testosterone administration might be helpful or might instead cause adverse effects.
 
Two articles in this issue of the Journal address these important issues.3,4 Wu et al.3 report on a population survey of 3369 men, 40 to 79 years of age, in eight European centers. Results of the survey with respect to subjects' general, sexual, physical, and psychological health were compared with morning measurements of total and free testosterone levels in the subjects' serum. Among many symptoms surveyed, three sexual symptoms (poor morning erection, low sexual desire, and erectile dysfunction) and three general symptoms (inability to perform vigorous activity, depression, and fatigue) were associated with low testosterone levels. Further analysis showed that the presence of at least three sexual symptoms in a man with a total testosterone level of less than 11 nmol per liter (3.2 ng per milliliter) could be used to define late-onset hypogonadism. This conclusion was validated in a second data set in the same study. These conclusions are a valuable addition to earlier research, as well as to society guidelines,5,6 which have also proposed the combination of symptoms and low testosterone levels to establish the diagnosis of late-onset hypogonadism. The difficulty with using symptoms alone to define late-onset hypogonadism was highlighted by the finding that more than 25% of men with normal testosterone levels had similar sexual symptoms.
 
Among older men with testosterone deficiency, can we replace testosterone in an effective and safe manner? Many studies involving limited numbers of men have shown that the administration of testosterone results in improved muscle mass and strength, increased bone mass, and other positive effects.7 None of the studies have been of sufficient size or duration to adequately address potential risks, such as the risk of prostate disease. The study by Basaria et al.4 was designed to assess whether leg-muscle strength in older men with severe limitations in mobility was increased as a result of testosterone administration. Community-dwelling men 65 years of age or older with a testosterone level of 100 to 350 ng per deciliter (3.5 to 12.1 nmol per liter) were randomly assigned to receive a transdermal gel containing testosterone (to achieve testosterone levels of 500 to 1000 ng per deciliter [17.4 to 34.7 nmol per liter]) or placebo. The 209 participants had a high prevalence of hypertension, diabetes, hyperlipidemia, and obesity. During the experimental phase, the testosterone group showed greater leg and arm strength than did the placebo group but also had higher rates of cardiovascular adverse effects. The excess of cardiovascular events in the testosterone group led the data and safety monitoring board to recommend early termination of the study. Of initial concern was the fact that 10 of the 106 men receiving testosterone had adverse cardiac events, as compared with 1 of the 103 men receiving placebo. Further investigation at the request of the data and safety monitoring board showed excesses of "cardiovascular-related" events in the testosterone group. These results are surprising, since many studies with cumulative numbers of subjects greater than those reported here have not detected substantial increases in cardiovascular risk during testosterone administration (including many studies in which subjects achieved the same or higher serum testosterone levels, some for longer periods of time).8 As the authors state, there is a clear possibility that their results are due to chance.
 
Many readers may disagree with the decision of the data and safety monitoring board to terminate the study early. Results of studies terminated early may differ from those of larger, longer-term studies. Also, readers will speculate that the higher rates of adverse events in the testosterone group may have been due to the fact that the two groups of men had different baseline characteristics, with a higher rate of hyperlipidemia and statin use and of hypertension in the testosterone group before the experimental interventions. To me, the decision of the data and safety monitoring board seems reasonable. For whatever reason, there were higher rates of cardiovascular disease in the group of men who were receiving testosterone in this study than in their counterparts who were receiving placebo.
 
Although this result sounds a note of caution in general concerning testosterone administration in older men, it certainly should not deter investigators from proceeding with additional, larger studies of testosterone administration in well-characterized groups of older men to more clearly outline benefits and risks. Similarly, it should not prevent clinicians from prescribing testosterone replacement for well-established late-onset hypogonadism, although it should provide some new caution about the administration of testosterone in older men who have an extensive history of cardiovascular disease and immobility.
 
Ultimately, we will need large, carefully designed trials of testosterone administration, perhaps along the lines of the Women's Health Initiative. Such trials should include a sufficient number of subjects to allow the assessment of key clinical outcomes, such as bone-fracture rates, muscle strength, and avoidance of falls, and an assessment of the role of testosterone replacement in the prevention of psychiatric disease, as well as the risks for prostate, cardiovascular, and other adverse outcomes. The numbers of older men receiving testosterone are large and increasing. We owe it to our patients and their families as well as to our physician colleagues to have much better data and guidelines for the administration of this critical hormone.  
http://www.youtube.com/watch?feature=player_embedded&v=I3ba3lnFHik

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #79 on: December 10, 2010, 02:34:19 pm »

I don't think anyone here is trying to 'bully' you, just giving sound advice.   Testosterone therapy is not something to take lightly.   If the numbers indicate that you don't need it, then you probably don't.

The numbers don't mean a thing if you feel different.  As a wise doctor told me once, "you treat the patient on not the guidelines on paper."
http://www.youtube.com/watch?feature=player_embedded&v=I3ba3lnFHik

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Offline Jeff G

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #80 on: December 10, 2010, 02:53:52 pm »
I was just wondering if you have had any therapy or counseling about this issue ? , you seem really fixated on it lately .
« Last Edit: December 10, 2010, 03:01:43 pm by jg1962 »
HIV 101 - Basics
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HIV Testing
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PEP and PrEP

Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #81 on: December 10, 2010, 11:29:11 pm »
a book that dive information on testosterone named "Testosterone."

http://www.testosteronewisdom.com/order.html

this gives the first twenty pages of the book.

http://issuu.com/nelsonvergel/docs/aatestosteronefirst20pages

« Last Edit: December 11, 2010, 06:07:50 pm by red_Dragon888 »
http://www.youtube.com/watch?feature=player_embedded&v=I3ba3lnFHik

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #83 on: December 13, 2010, 09:57:46 pm »
http://www.google.com/url?sa=X&q=http://herbalsupplementtestosterone.blognub.com/herbal-supplement/what-you-should-know-about-low-testosterone-levels-in-men-know/&ct=ga&cad=CAcQAhgAIAIoATAAOABA4c-a6ARIAVAAWABiAmVu&cd=U6TY-DXC0d0&usg=AFQjCNGay5D-mKGz7_nBiiya2yg0zrB3Gw

What you should know about low testosterone levels in men know ...
By bruno_mama
Traditional testosterone replacement therapy, the oral or the effort is injected synthetic testosterone is a risk of prostate cancer, prostate cancer, heart disease and hypertension. So whata male natural testosterone replacement? ...
http://www.youtube.com/watch?feature=player_embedded&v=I3ba3lnFHik

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #85 on: December 13, 2010, 10:20:07 pm »
ANDORPAUSE (MALE MENOPAUSE) MALE SEXUAL DYSDFUNCTION, ERECTILE DYSFUNCTION
Publication Date: December 13, 2010 - 5:35pm
Updated: December 13, 2010 - 5:35pm
News Section:Doctor
Sexual disorder in men can be one of men's worst experiences
PART ONE
By: Dr. Walter Brumskine
A man, 50 years old, came to see me a couple of months ago. He was gay and complained of having marked decrease in sexual desire and ability. This is of course, a very sensitive and embarrassing subject for any man, and the patient had difficulty in discussing his problem with me. He wanted to know if this was a normal aging process or if it could be his andorpause since he had read about male menopause before in the OBSERVER DOCTOR.

Generally, men actually do not see a decrease in sexual desire and feeling as they get older; it is not always age but can be due to other causes. It just takes longer sometimes for older men to obtain an erection. What a younger man can do in thirty seconds, it may take ten to fifteen minutes for an older man to achieve an erection and sensitivity. It could be a lack of enough manual stimulation as well.

How Do Men Change Physically With Age And How Does That Affect Sex?

Men, as they age, also experience a loss of androgens (male sex hormone produce by the testis) in the body which can affect your sex drive. You could also be experiencing a lack of testosterone (another male sex hormone, also produced by the testis). You may also suffer erectile dysfunction, which is also common after the age 50.

Is Advancing In Age Affecting My Sex Drive?

When a man cannot get an erection to have sex or cannot keep an erection long enough to finish having sex, it is called erectile dysfunction. Erectile dysfunction can occur at any age, but it is more common in men older than 65 years.

What Is Erectile Dysfunction?

It is possible that it could be andropause as the symptoms are symptoms of male menopause that may include lethargy or decreased energy, decreased libido or interest in sex, erectile dysfunction with loss of erections, muscle weakness and aches, inability to sleep, hot flashes, night sweats, depression, infertility and thinning of bones or bone loss.

If you are experiencing a number of these along with sexual issues, please talk it over with your doctor.

You should go to your doctor or an urologist and tell him about these concerns. Go with a list of questions that you need answered, so that you can make sure that you get all the information you deserve and he has to listen to you. If you still feel uncomfortable, go and obtain a second opinion from another doctor you do not normally see. Ask for formation on erectile dysfunction. Talk about medications (Viagra) if you are curious about that route.

Above all, do not worry. While it is not age alone that causes these symptoms but a number of physical reasons, you may have nothing to worry about. I am sure you will get the medical care you need to get back in the saddle again.

Sexual Desire And Ability

Erectile dysfunction is significantly attributed to physiological causes; psychological factors include fear of our female partners, depression, lack of self esteem, and cluelessness as to what to do with certain parts of the female anatomy.

A positive thought-process and emotions can help your mental state of being, consequently aiding in a better performance during coitus, Viagra only treat one symptom of the male menopause or andropause, and will not work if the desire is not there.

Erectile dysfunction is significantly attributed to physiological causes; psychological factors include fear of our female partners, depression, lack of self esteem, and cluelessness as to what to do with certain parts of the female anatomy. A positive thought-process and emotions can help your mental state of being, consequently aiding in a better performance during coitus, Viagra only treat one symptom of the male menopause or andropause, and will not work if the desire is not there.

A man without andropause can have a constant, steady flow of blood to the penile arteries in a good amount. The more blood that flows down there, the harder and longer your erection will be.

Viagra and its generic version work differently from testosterone replacement therapy. Viagra acts on the penis by maintaining an erection; testosterone works on the whole body and all aspects of sexual response. Testosterone is the hormone of sexual desire in both men and women. As a result, if testosterone levels are low, so is the desire for sex. Impotence or erectile dysfunction is a complex problem that requires a thorough psychological and physical examination.

Physicians may use a combination of approaches to treat erectile dysfunction. However, Viagra and generic version may treat only one part of man erection. Testosterone replacement therapy not only improves a man's erectile quality; it can improve sexual desire and prevent debilitating diseases like osteoporosis and cardiovascular disease.

Viagra and its generic versions plus testosterone are the logical and affirmative solution to the widespread cause of erectile dysfunction, the andropause.

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #86 on: December 13, 2010, 10:21:32 pm »
What you should know about low testosterone levels in men know
December 13th, 2010 by bruno_mama

Low levels of testosterone in men and depression were taken in conjunction with an increased risk of heart disease, impotence, osteoporosis. Symptoms of low testosterone in men include low sex drive, muscle weakness, fatigue and others.


Traditional testosterone replacement therapy, the oral or the effort is injected synthetic testosterone is a risk of prostate cancer, prostate cancer, heart disease and hypertension.

So whata male natural testosterone replacement?

Except in cases of testicular tissue or gland dysfunction of the male body produces testosterone naturally, during his lifetime. What is most men are the symptoms associated with decreased production of testosterone, testosterone to normal levels or below.

As a boy get that testosterone levels return to normal? Is there such a thing as a natural male testosterone replacement Therapy?

Stress, alcohol consumption, smoking, obesity and physical inactivity can inhibit the body's ability to produce testosterone. With anabolic steroids, such as synthetic testosterone, for sports performance or hormone replacement therapy reduces the production of testosterone your body is.

Thus, questions of lifestyle can lead to low testosterone in men. To increase the ability to naturally produce the body> Testosterone, men should address these issues lifestyle. This therapy could be a step in a male's natural testosterone replacement.

Eating large amounts of fried foods and fatty dairy products (such as whole milk and cheese) can lead women to be overweight, which (see above or men) can cause low levels of testosterone in too much caffeine and sugar on top stimulate the adrenal glands and women can lead to low testosterone in men o.

Thus, a healthy dietimportant. Remember to take vitamins. Zinc is particularly important in the production of testosterone.

What natural supplements male testosterone replacement?

Remember that just because a supplement is "natural" does not necessarily mean it is safe. Some herbal medicines have undesirable side effects and can also cause serious health risks.

Tribulus terrestris is one of the safest, according to research carried out in% Bulgaria may increase levels of testosterone and more like 40 'was used by athletes such as synthetic testosterone, the desire to improve their performance without steroids.

So, Tribulus terrestris, in contrast, testosterone levels in men and may better integrate the natural male testosterone replacement low.

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #87 on: December 13, 2010, 10:25:24 pm »
Side effects of testosterone replacement therapy

Testosterone replacement therapy is a method of treatment that is used in cases when it is necessary to restore sexual functioning, increase libido, prevent osteoporosis and optimize bone density, restore the strength of the muscles and to improve mental functioning. The greatest majority of these problems is usually caused by decreased levels of testosterone, and there is a number of possible reasons that may be responsible for that. However, this therapy helps with all these problems by increasing the levels of testosterone and by normalizing them. Besides testosterone, the levels of other hormones that are affected by this one (DHT and estradiol, among others) are also normalized.

Are there any side effects of testosterone replacement therapy?

First of all, it is important to know that no matter how helpful this therapy might seem, it is not a good choice for everyone. People who are at higher risk of not reacting well to this therapy are those who suffer from prostate cancer, because testosterone replacement therapy may cause the growth of the prostate. Due to this possibility, all the patients have to undergo prostate screening in advance.

Despite the fact that this therapy is generally considered safe, there are some side effects that may occur, although it is practically impossible to predict whether or not they will appear in a particular case, and how they will manifest. However, if a person notices oily skin or presence of acne, enlargement of breasts, decrease in the size of testicles, as well as mild fluid retention, it is recommended to contact the doctor. Swelling of the prostate, sleep disorder and emotional instability are also possible, which is why the person should be well acquainted with all the possibilities.

Besides this, some side effects may be related only to a particular form of this therapy. That way, the signs of liver toxicity have been reported in cases of those who used oral testosterone replacement, although the fact is that all the manufacturers mention liver problems as a possible side effect. Men who plan to have children in the future should bear in mind that there is a possibility of experiencing infertility, which may be only temporary, but which may also be permanent. A condition known as polycythemia is one of the serious side effects and it is much more likely to occur in older men. This condition is characterized by the increase in the mass of the red blood cells and levels of hemoglobin, which increases the risks of heart attacks, strokes and similar problems.

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #88 on: December 18, 2010, 04:27:00 am »
http://articledashboard.org/expectancy-from-male-hormone-replacement-therapy-programme

When you start any male hormone replacement therapy program, most guys ask them selves if they have guy menopause signs. Symptoms of male menopause, also called andropause, include reduced mental explosiveness, decreased power and strength, less desire for activity, decreased muscle, greater body fat, night sweats or trouble sleeping, mild in order to moderate depressive disorders and becoming easily irritated and reduced sexual desire.

If you have one or more of such symptoms, hormone replacement remedy can make you seem like yourself once again.

What does a thorough Male hormone replacement Program Consist of?
The basic male hormone replacement software includes testosterone and thyroid supplements. HGH (human growth hormone) doubles as an optionally available component to cure. Please understand that HGH could be expensive, but will provide a visible boost to supplement the testosterone premature ejaculation pills.

How long does will it take for me in order to feel far better?
Most guys notice a change in their energy and experience better from the first 3 weeks of cure.

1st week
- You will observe a change in your emotional quickness along with clarity.

2nd week
: You can expect your efforts levels as well as endurance to improve. One e-book on the subject known as the change within energy while, “getting your MoJo rear.” If you have been experiencing swift changes in moods and sweating prior to remedy, you can expect these kinds of symptoms vanish within the 1st week.

3rd week
- Your libido should boost. You should experience an increase in early morning erections and perhaps night goals and morning fantasies. Exercising will start to grow to be easier and result will start to show.

The Following Months:
In the next couple of weeks, you should start to be able to feel like yourself again. You will end up energized to see improvements with your mood along with sense regarding well-being. You will have an increased quality of sleep in addition to improved sex drive and heightened sexual performance. With appropriate diet and exercise, you will see an increase in lean muscle and an increase in muscle durability.

Other benefits of hormone replacement include improved bone density and an improved heart. Osteoporosis can be an increasing symptom in men along with testosterone remedy has been shown to increase bone vitamin density.

Do you want to Start a Male hormone replacement Therapy Plan?
If male hormone replacement treatments sounds like it could benefit you, you can search online for a male hormone replacement therapy system. An andropause treatment specialist will be able to answer questions and enable you to identify your physician near you. Laboratory testing is going to be arranged in close proximity to where you live. After those email address particulars are available a consultation will be constructed with a men hormone remedy doctor.

A high level candidate for male hormone replacement therapy, your medical professional will focus on your therapies, which include common tablets or perhaps capsules, injections or skin medications. Your doctor may follow-up with you on a regular basis to monitor change and more optimize treatment.

For further detail regarding Menopause for Men or Testosterone Replacement Therapy and Male Hormone replacement please visit any of given link.

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #89 on: December 18, 2010, 04:29:56 am »
http://familyhealth365.blogspot.com/2010/12/could-hormone-replacement-therapy-help.html

Could hormone replacement therapy help the sex drives of very old men?


The very oldest men are still interested in sex but illness and a lack of opportunity may be holding them back, Australian researchers reported on Monday.

The "male" hormone testosterone was clearly linked with how often a man over 75 had sex, and doctors need to do more studies to see if hormone replacement therapy might benefit older men, the researchers said.

Zoe Hyde of the University of Western Australia and colleagues surveyed more than 2,700 men aged 75 to 95 for their study, published in the Annals of Internal Medicine.

They asked a range of questions about health, relationships and sexual activity.

"The older men were, the less likely they were to be sexually active, but sex remained at least somewhat important to one fifth of men aged 90 to 95 years, refuting the stereotype of the asexual older person," they wrote in their report.

"Of those who were sexually active, more than 40 percent were dissatisfied with the frequency of sexual activity, preferring sex more frequently."

More than 30 percent of the men reported some sort of sexual activity in the past year, but more than 48 percent said sex was important, suggesting many of the men wanted to have sex but could not.

Age was a factor but so were testosterone levels, the lack of an interested partner, and various diseases from diabetes to prostate cancer.

More than 40 percent of the men who had not had sex recently said they were not interested.
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #90 on: December 18, 2010, 04:32:06 am »
Requirement through male hormone replacement therapy programme

http://www.articlejug.com/requirement-through-male-hormone-replacement-therapy-programme/

Before you begin a male hormone replacement therapy software, most guys ask them selves if they have man menopause signs or symptoms. Symptoms of men menopause, also known as andropause, include decreased mental quickness, decreased electricity and power, less desire for activity, lowered muscle, elevated body fat, night sweats or sleep disorders, mild in order to moderate depression and irritability and reduced sexual drive.

If you have one or more of these symptoms, hormone replacement treatments can make you think that yourself again.

What does a thorough Male hormone replacement Program Include?
The basic male hormone replacement program includes androgen hormone or testosterone and thyroid gland supplements. Human growth hormone (human growth hormone) may also be used as an optional component to treatment. Please remember that HGH could be expensive, yet will provide a noticeable boost to be able to supplement the particular testosterone premature ejaculation pills.

How long really does will it require me to feel far better?
Most guys notice a modification of their energy levels and experience better inside first 3 weeks of treatment.

1st week
- You will see a change in your mind quickness along with clarity.

2nd week
: You can expect your energy levels as well as endurance to improve. One guide on the subject known the change in energy as, “getting your MoJo back.” If you’ve been experiencing mood swings and night sweats prior to therapy, you can expect these types of symptoms disappear within the very first week.

3rd week
* Your sex drive should enhance. You should knowledge an increase in early morning erections and perhaps night goals and evening fantasies. Physical exercise will start to grow to be easier along with result will begin to show.

The next Months:
Over the next few weeks, you should start in order to feel like on your own again. You may be energized and find out improvements in your mood as well as sense of well-being. You will have an improved quality of sleep along with improved libido and performance. With healthy diet and exercise, you will observe an increase in lean muscle and an increase in muscle power.

Other important things about hormone replacement include greater bone density and also an improved heart. Osteoporosis is definitely an increasing symptom in men along with testosterone remedy has been shown to enhance bone nutrient density.

Are You Ready to Start a new Male hormone replacement Therapy Plan?
If male hormone replacement treatments sounds like it could benefit you, searching online to get a male hormone replacement therapy program. An andropause treatment specialist can answer your queries and enable you to identify a health care provider near you. Research laboratory testing will likely be arranged in close proximity to where you live. Once those results are available an appointment will be made with a men hormone cure doctor.

A high level candidate with regard to male hormone replacement therapy, your doctor will talk about your treatment options, which include oral tablets or even capsules, shots or topical creams. Your doctor may follow-up with you frequently to monitor change and additional optimize therapy.

For further information about Menopause for Men or Testosterone Replacement Therapy and Male Hormone Therapy please visit any of given link.

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Offline Miss Philicia

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #91 on: December 18, 2010, 04:40:45 am »
Have you considered starting a blog?
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #92 on: December 23, 2010, 07:09:16 pm »
http://www.wellchosen.net/2010/testosterone-gel-overview/

Testosterone Gel: Overview

If your lifestyles doesn’t allow you to spend as much time at the gym as you’d like, or eat the foods high in monosaturated fat that you need for a naturally high level of testosterone, a natural gel provides an alternative that is normally completely safe (the only health risk attributed to testosterone gel is skin irritation) while still in a different league from synthetic hormones like anabolic steroids. It is a safe, easily available online, convenient way to increase the hormone production.

Usage of Testosterone Gel

Apply to arms, shoulder or abdomen (NOT to the genital area as it may irritate the sensitive genital skin). Make sure your skin is dry and clean before applying. No need to rub it in – it will penetrate the skin rapidly by itself and takes only a few minutes to dry. Let it dry before getting dressed. You may shower as soon as one hour after application of Testosterone gel, but it is better to wait six hours in order to allow the gel to be fully absorbed by the skin. Avoid skin-to-skin contact with others until application has dried (a few minutes).

Who Should Use Testosterone Gel?

You should only proceed with treatment for testosterone deficiency when the condition has been confirmed by your doctor through proper medical tests. Symptoms relating to testosterone deficiency include reduced muscle mass and strength, a decrease in sexual desire (libido) and a diminishing ability to have an erection. Increased irritability or depression, fatigue, decreased concentration and loss of typical male pattern hair growth are further signs of low testosterone levels
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #93 on: December 24, 2010, 06:24:59 am »
http://www.ncbi.nlm.nih.gov/pubmed/21154195

Horm Metab Res. 2010 Dec 10. [Epub ahead of print]

Effect of Vitamin D Supplementation on Testosterone Levels in Men.
Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B, Wehr E, Zittermann A.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Austria.

Abstract
The male reproductive tract has been identified as a target tissue for vitamin D, and previous data suggest an association of 25-hydroxyvitamin D [25(OH)D] with testosterone levels in men. We therefore aimed to evaluate whether vitamin D supplementation influences testosterone levels in men. Healthy overweight men undergoing a weight reduction program who participated in a randomized controlled trial were analyzed for testosterone levels. The entire study included 200 nondiabetic subjects, of whom 165 participants (54 men) completed the trial. Participants received either 83 μg (3 332 IU) vitamin D daily for 1 year (n=31) or placebo (n=23). Initial 25(OH)D concentrations were in the deficiency range (<50 nmol/l) and testosterone values were at the lower end of the reference range (9.09-55.28 nmol/l for males aged 20-49 years) in both groups. Mean circulating 25(OH)D concentrations increased significantly by 53.5 nmol/l in the vitamin D group, but remained almost constant in the placebo group. Compared to baseline values, a significant increase in total testosterone levels (from 10.7±3.9 nmol/l to 13.4±4.7 nmol/l; p<0.001), bioactive testosterone (from 5.21±1.87 nmol/l to 6.25±2.01 nmol/l; p=0.001), and free testosterone levels (from 0.222±0.080 nmol/l to 0.267±0.087 nmol/l; p=0.001) were observed in the vitamin D supplemented group. By contrast, there was no significant change in any testosterone measure in the placebo group. Our results suggest that vitamin D supplementation might increase testosterone levels. Further randomized controlled trials are warranted to confirm this hypothesis.

© Georg Thieme Verlag KG Stuttgart · New York.
PMID: 21154195 [PubMed - as supplied by publisher]

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Offline Miss Philicia

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #94 on: December 24, 2010, 10:03:13 am »
I wasn't sure whether or not this should go in this thread or the youtube thread:

http://www.youtube.com/watch?v=ZBmZn4jFfAA
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #95 on: December 25, 2010, 09:22:36 am »
I wasn't sure whether or not this should go in this thread or the youtube thread:

http://www.youtube.com/watch?v=ZBmZn4jFfAA
Darling, sweet heart, beautiful...  I get the sense you are troubled.  I hope you are well and may many good things come your way.  Merry Christmas, Happy New Year and All the Best.
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Offline Miss Philicia

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #96 on: December 25, 2010, 10:37:25 am »
Darling, sweet heart, beautiful...  I get the sense you are troubled.

You may wish to discuss psychological projection with your therapist.  When's your next session?
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #97 on: December 26, 2010, 04:35:30 pm »
You may wish to discuss psychological projection with your therapist.  When's your next session?
lol

http://www.youtube.com/watch?v=8hGvQtumNAY&feature=related
« Last Edit: December 26, 2010, 04:39:08 pm by red_Dragon888 »
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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #98 on: December 30, 2010, 05:34:35 am »
http://pinoypen.com/testosterone-and-impotence-how-are-they-related-18748

Testosterone and Impotence: How are they related?

29.12.2010 | Author: galenakarsson | Posted in Health & Fitness
Recent studies show baffling figures about ED. The studies indicate that approximately 152 million men all over the world have to confront male impotence or erectile dysfunction.  Statistics show that, of 152 million men, about 20 million are old men and young men. In U.S alone, there are around 20 million men affected by male impotence. Additionally, studies point out that about 5% of 40 year old men and 15-25% of 65 years and above encounters erection problems while making love with their partner. Quite simply, owing to the conditions, men suffering from ED are not able to satisfy their partner in the bed.

Psychological impact due to ED

Erectile dysfunction (ED) is not an ailment to fear about – as it was few decades back. However still, it is one of the ever growing problems ignored by many individuals. Erectile dysfunction, also referred as men impotence, is an inability of men to perform sexual activity with high passion, or inability to keep up erection during copulation. As per some studies, over 100 million men around the world suffer from erectile dysfunction (ED). Erectile dysfunction is just a periodic problem for some men. However for many, it is an issue that makes a negative impact on mental health, especially, the thought of a fizzled out love making session.

The thoughts of powerlessness that flood while making love could dent confidence of a person to an irreparable and irreversible extent. Still worse, the agonizing thoughts are capable of impairing both personal life and work life.

However, sulking over the erectile dysfunction issue would not help the cause. Above all, it would heap up of apprehensions and worries that could shackle a person’s thinking ability. So taking a help in form of medication or seeking counseling is the best approach to rid of erectile dysfunction.

There are could be a number of factors that could cause male impotence. They are as follows:

•Low testosterone
•Stress
•Health related problems such as high blood pressure, diabetes, and heart disease
•Psychological issue such as depression
Among them, low testosterone is one of prime reasons for causing ED.

How low testosterone results in ED problems?

Testosterone plays a crucial role in a normal erectile process. Less testosterone level would result in a condition referred as hypogonadism, or testosterone deficiency. Eventually, it could result in erectile dysfunction. In such cases, testosterone replacement therapy is one of the best ways to diagnose hypogonadism to conquer the conditions of erectile dysfunction. Around 5% of men choose testosterone replacement therapy for ED problem. This therapy begins with a blood test to detect testosterone levels. People with erectile dysfunction have shown a noticeable improvement after undergoing testosterone replacement therapy.

However besides low level of testosterone, there may be other factors which may lead to ED. Hence, testosterone therapy for such patients with erectile dysfunction problem may or may not be work.

To sum up

Not all men with a slight drop in testosterone levels suffer from erectile dysfunction. On the other hand, testosterone replacement therapy has worked for some men with normal testosterone levels. Therefore, level of testosterone plays a key role in deciding erectile dysfunction; however, it differs from one individual to another.

Author BIO

Galena Karsson, a general practitioner, is also an acclaimed writer famous for her tips on men’s impotency. Her articles on various ED medications such Kamagra have helped many to lead a normal life again.

Article Source

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Offline red_Dragon888

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Re: AMEN to the Hard-Ons... WARNING... Strong language here...
« Reply #99 on: December 30, 2010, 05:37:25 am »
http://www.ihealthdirectory.com/testosterone-levels-in-women/

Testosterone levels in women

Testosterone is an androgen. It is a steroid hormone that is associated with male sexuality and development. This hormone is responsible for the development of male characteristics like male sex organs, deep voice, facial hair, etc. However this hormone is present in women, too. Testosterone is present in the testes of men and the ovaries of women. A woman’s testosterone levels are very low when compared to that of a man. However, this hormone does play an important role in both men and women. It is essential for proper functioning of the brains, bone and muscle mass, fat distribution, energy production and sexual functioning.

Low testosterone levels in women can cause several problems. This hormone is essential for maintaining bone mass, density and strength. Reduction in testosterone levels can put women at risk of developing osteoporosis. Low testosterone levels in women can also affect libido or sex drive. This hormone is essential for maintaining good sexual function and sex drive. Testosterone in women is also responsible for maintaining muscle strength and mass. In general, sufficient testosterone levels are essential for overall health and well being.

Excess of women’s testosterone levels can also cause several health problems. Since testosterone is a male hormone, women who have to much of this hormone tend to show certain male characteristics like male pattern hair growth, hirsutism, increased muscle mass or a deepening voice. In general, testosterone levels in women tend to increase around puberty and then decline. As a woman approaches menopause, her testosterone levels may reduce drastically.

High testosterone levels are associated with health problems like Cushing syndrome, polycystic ovarian syndrome, adrenal hyperplasia and insulin resistance. High testosterone levels can greatly reduce fertility in women. So, if you are of child bearing age and finding it hard to conceive, it is essential to make sure that your testosterone levels are normal. Some studies have shown that high testosterone levels are associated with increased risk of cardiovascular diseases, as well.

Women’s testosterone levels stand at around 40 to 50 g/dl around age 15 and increases to 70 ng/dl around the 20s. Post-menopausal women have anywhere between 7 to 40 ng/dl of testosterone

There are several ways to determine a woman’s testosterone level. Blood and saliva samples are commonly used to determine the levels of testosterone. Blood tests involve analyzing serum for total testosterone. Results of these tests include the testosterone that is bound to proteins and cannot be used by the body. Saliva tests are more practical and accurate. It measures the amount of free testosterone that is actually available for use by the body.

If a woman is found to have low testosterone levels, testosterone replacement therapy may be recommended. This involves using testosterone in the form of creams, gels, capsules, patches or even injections. Oral testosterone supplements are easy to use. They contain synthetic bioidentical testosterone. Testosterone creams can be used to deal with vaginal dryness and weakness of vaginal muscles. There are testosterone patches which release testosterone though the skin in small doses. Intramuscular injection of testosterone is another method used to deal with testosterone deficiency. Injections of 50 to 100 mcg testosterone monthly may be recommended.

In women with high testosterone levels, treatment is aimed at combating the symptoms. For instance, laser therapy can be used to remove excess hair on the face and chest. Lifestyle modifications, weight reduction, healthy diet, exercise and stress management techniques can help manage high testosterone levels to a good extent.

If you are experiencing any of the symptoms listed above and think you may have issues with testosterone levels, it would be a good idea to see your doctor. He or she can do the necessary testing to determine if that is causing the problem and be able to provide effective treatment. As with anything, the earlier a problem is identified, the better the prognosis so see your doctor if you suspect abnormal testosterone levels.

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